Synthesis of the 4-hydroxyimino-3-carboxamide-2-quinolone with a new heterocyclization mechanism of the reaction between carbon suboxide and 2-aminobenzamidoxime

被引:1
|
作者
Secci, D
Chimenti, F
Lavagna, SM
Bonsignore, L
Manna, F
Alcaro, S
Bolasco, A
机构
[1] Univ Cagliari, Dipartimento Farmaco Chim Tecnol, I-09124 Cagliari, Italy
[2] Univ Rome La Sapienza, Dipartimento Chim & Tecnol Sostanze Biologicament, I-00185 Rome, Italy
[3] Univ Catanzaro Magna Graecia, Dipartimento Sci Farmaco Biol Complesso Nini Barb, I-88021 Roccelletta Borgia, Italy
关键词
conformational search; charge calculation; oxime;
D O I
10.3987/COM-00-9032
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis of the 4-hydroxyimino-3-carboxamide-2- quinolone with a new heterocyclization mechanism of the reaction between carbon suboxide and 2-aminobenzamidoxime is reported. Its formation is also supported by charge calculations.
引用
收藏
页码:2789 / +
页数:6
相关论文
共 50 条
  • [31] ON THE REACTION BETWEEN POTASSIUM ETHOXIDE AND 3-AMINO-4-BENZOYLFURAZAN - THE CRYSTAL-STRUCTURE OF THE INTERMEDIATE, 5-PHENYL-1,2,4-OXADIAZOLE-3-CARBOXAMIDE
    VITERBO, D
    CALVINO, R
    SERAFINO, A
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1980, (07): : 1096 - 1098
  • [32] Heterocyclization of Isoniazid: Synthesis and Antimicrobial Activity of Some New Pyrimidine, 1, 3-Thiazole, 1, 2, 4-Thiadiazole, and 1, 2, 4-Triazole Derivatives Derived from Isoniazid
    Farhan, Mona E.
    Assy, Mohammed G.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2019, 62 (02): : 171 - 180
  • [34] Reaction mechanism between carbon and CaO - SiO 2-Al 2 O 3-Na 2 O slag system during continuous casting process
    Sun, Ruijing
    Wu, Jinhu
    Wang, Hui
    Zhang, Wei
    Liu, Chao
    Gu, Shaopeng
    Xing, Weihong
    Yu, Liang
    JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T, 2024, 30 : 8882 - 8893
  • [35] Synthesis, Characterization and Preliminary Screening of New N-Substituted-8-Methyl-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Anticancer Agents
    Altaher, Dania
    Zalloum, Hiba
    Sweidan, Kamal
    Sabbah, Dima A.
    AlSalamat, Husam
    Sunjuk, Mahmoud
    Isleem, Reem
    CURRENT ORGANIC SYNTHESIS, 2025, 22 (02) : 270 - 279
  • [36] Computational insights into the reaction mechanism of the synthesis of quinazoline derivatives via the cyclocondensation reaction between methyl 2-amino-4-(2-diethylaminoethoxy)-5-methoxybenzoate and formamide
    Tenambo, Ariane Pouyewo
    Adjieufack, Abel Idrice
    Ewonkem, Monique Bassomo
    Mbah, Maraf Bake
    Abouem, Auguste
    Ndassa, Ibrahim Mbouombouo
    COMPUTATIONAL AND THEORETICAL CHEMISTRY, 2024, 1235
  • [37] SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL SCREENING OF NEW N-SUBSTITUTED-7-CHLORO-4-HYDROXY-2-QUINOLONE-3-CARBOXAMIDES AS PROMISING ANTICANCER AGENTS
    Al-Zuheiri, Aya Mohammed Kheir
    Sweidan, Kamal
    Harb, Mohammed Kamal
    Bardaweel, Sanaa K.
    Sunjuk, Mahmoud
    Sabbah, Dima A.
    HETEROCYCLES, 2022, 104 (07) : 1303 - 1314
  • [38] Mechanism of heterogeneous reaction between gaseous elemental mercury and H2O2 on Fe3O4 (110) surface
    Zhou, Changsong
    Yang, Hongmin
    Chen, Jiamin
    Qi, Dongxu
    Sun, Jiaxing
    Mao, Lin
    Song, Zijian
    Sun, Lushi
    COMPUTATIONAL AND THEORETICAL CHEMISTRY, 2018, 1123 : 11 - 19
  • [39] A convenient preparation of 4,8-dimethoxy-3-substituted-2(1H)-quinolones by an electrophilic reaction through base-induced deprotonation and its synthetic application for the synthesis of new alkaloids, 3,4,8-trimethoxy-2(1H)-quinolone and 3-formyl-4,7,8-trimethoxy-2(1H)-quinolone (glycocitridine)
    Tagawa, Y
    Kawaoka, T
    Goto, Y
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1997, 34 (06) : 1677 - 1683
  • [40] In-situ synthesis and reaction mechanism of β-SiAION in the Al-Si3N4-Al2O3 composite material
    Jiang, Peng
    Wu, Xiaofang
    Xue, Wendong
    Chen, Junhong
    Wang, Wei
    Li, Yong
    CERAMICS INTERNATIONAL, 2017, 43 (01) : 1335 - 1340