Ever since its emergence Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) has caused an enormous amount of morbidity and mortality. Pregnancy being a high risk state is also being affected by this lethal pandemic causing an increased risk of rising maternal mortality. The treatment strategies for managing COVID-19 in pregnant female remains limited with no definite treatment available. With the growing evidence of Lymphocytopenia in COVID-19 there has been a emergence of immunoglobulin (IVIg) as a relatively safe treatment option in immunodeficient states such as pregnancy. Though research remains limited in the aspect of immunoglobulin therapy in pregnancy a risk versus benefit ratio might allow use of immunoglobulin therapy. We present a case of COVID-19 associated cytokine storm with lymphocytopenia in a Pregnant female which was successfully treated with immunoglobulin therapy.
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Columbia Mailman Sch Publ Hlth, Ctr Infect & Immun, New York, NY 10032 USAStanford Univ, Sch Med, Div Infect Dis & Geog Med, Stanford, CA 94305 USA
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Altinbas Univ, Fac Med, Bahcelievler Med Pk Hosp, Div Rheumatol,Dept Internal Med, Istanbul, TurkeyAltinbas Univ, Fac Med, Bahcelievler Med Pk Hosp, Div Rheumatol,Dept Internal Med, Istanbul, Turkey
Soy, Mehmet
Keser, Gokhan
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Ege Univ, Fac Med, Dept Internal Med, Div Rheumatol, Izmir, TurkeyAltinbas Univ, Fac Med, Bahcelievler Med Pk Hosp, Div Rheumatol,Dept Internal Med, Istanbul, Turkey
Keser, Gokhan
Atagunduz, Pamir
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Marmara Univ, Fac Med, Dept Internal Med, Div Rheumatol, Istanbul, TurkeyAltinbas Univ, Fac Med, Bahcelievler Med Pk Hosp, Div Rheumatol,Dept Internal Med, Istanbul, Turkey
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Huathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
Hubei Clin Med Ctr Cell Therapy Neoplast Dis, Wuhan, Peoples R ChinaHuathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
Tang, Lu
Yin, Zhinan
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Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Inst Translat Med, Zhuhai, Peoples R China
Jinan Univ, Fac Med Sci, Biomed Translat Res Inst, Guangzhou, Peoples R ChinaHuathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
Yin, Zhinan
Hu, Yu
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Huathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
Hubei Clin Med Ctr Cell Therapy Neoplast Dis, Wuhan, Peoples R ChinaHuathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
Hu, Yu
Mei, Heng
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Huathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
Hubei Clin Med Ctr Cell Therapy Neoplast Dis, Wuhan, Peoples R ChinaHuathong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Hematol, Wuhan, Peoples R China
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Boston Childrens Hosp, Boston, MA USA
Harvard Med Sch, Boston, MA 02115 USABoston Childrens Hosp, Boston, MA USA
Henderson, Lauren A.
Canna, Scott W.
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UPMC Childrens Hosp Pittsburgh, Pittsburgh, PA USA
Univ Pittsburgh, Pittsburgh, PA USABoston Childrens Hosp, Boston, MA USA
Canna, Scott W.
Schulert, Grant S.
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Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA
Univ Cincinnati, Coll Med, Cincinnati, OH USABoston Childrens Hosp, Boston, MA USA
Schulert, Grant S.
Volpi, Stefano
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IRCCS Ist Giannina Gaslini, Ctr Autoinflammatory Dis & Immunodeficiency, Genoa, Italy
Univ Genoa, Genoa, ItalyBoston Childrens Hosp, Boston, MA USA
Volpi, Stefano
Lee, Pui Y.
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Boston Childrens Hosp, Boston, MA USA
Harvard Med Sch, Boston, MA 02115 USABoston Childrens Hosp, Boston, MA USA
Lee, Pui Y.
Kernan, Kate F.
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UPMC Childrens Hosp Pittsburgh, Pittsburgh, PA USA
Univ Pittsburgh, Pittsburgh, PA USABoston Childrens Hosp, Boston, MA USA
Kernan, Kate F.
Caricchio, Roberto
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Temple Univ Hosp & Med Sch, Philadelphia, PA 19140 USA
Lewis Katz Sch Med, Philadelphia, PA USABoston Childrens Hosp, Boston, MA USA
Caricchio, Roberto
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Mahmud, Shawn
Hazen, Melissa M.
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Boston Childrens Hosp, Boston, MA USA
Harvard Med Sch, Boston, MA 02115 USABoston Childrens Hosp, Boston, MA USA
Hazen, Melissa M.
Halyabar, Olha
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Boston Childrens Hosp, Boston, MA USA
Harvard Med Sch, Boston, MA 02115 USABoston Childrens Hosp, Boston, MA USA
Halyabar, Olha
Hoyt, Kacie J.
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Boston Childrens Hosp, Boston, MA USA
Harvard Med Sch, Boston, MA 02115 USABoston Childrens Hosp, Boston, MA USA
Hoyt, Kacie J.
Han, Joseph
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Icahn Sch Med Mt Sinai, New York, NY 10029 USABoston Childrens Hosp, Boston, MA USA
Han, Joseph
Grom, Alexei A.
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Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA
Univ Cincinnati, Coll Med, Cincinnati, OH USABoston Childrens Hosp, Boston, MA USA
Grom, Alexei A.
Gattorno, Marco
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IRCCS Ist Giannina Gaslini, Ctr Autoinflammatory Dis & Immunodeficiency, Genoa, Italy
Univ Genoa, Genoa, ItalyBoston Childrens Hosp, Boston, MA USA
Gattorno, Marco
Ravelli, Angelo
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Univ Genoa, Genoa, Italy
IRCCS Ist Giannina Gaslini, Clin Pediat & Reumatol, Genoa, ItalyBoston Childrens Hosp, Boston, MA USA
Ravelli, Angelo
De Benedetti, Fabrizio
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Osped Pediat Bambino Gesu, Rome, ItalyBoston Childrens Hosp, Boston, MA USA
De Benedetti, Fabrizio
Behrens, Edward M.
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Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USABoston Childrens Hosp, Boston, MA USA
Behrens, Edward M.
Cron, Randy Q.
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Univ Alabama Birmingham, Childrens Alabama, Birmingham, AL USABoston Childrens Hosp, Boston, MA USA
Cron, Randy Q.
Nigrovic, Peter A.
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Harvard Med Sch, Boston, MA 02115 USA
Brigham & Womens Hosp, Boston Childrens Hosp, 75 Francis St, Boston, MA 02115 USABoston Childrens Hosp, Boston, MA USA