HOMOMERIC AND HETEROMERIC RECEPTOR COMPLEX FORMATION OF BONE MORPHOGENETIC TYPE I RECEPTORS ALK2 AND ALK3

被引:0
|
作者
Traeger, Lisa [1 ]
Gallitz, Inka [1 ]
Sekhri, Rohit [1 ]
Baeumer, Nicole [2 ]
Kuhlmann, Tanja [3 ]
Kemming, Claudia [3 ]
Bartnikas, Thomas B. [4 ]
Steinbicker, Andrea U. [1 ]
机构
[1] Univ Hosp Muenster, Dept Anesthesiol Intens Care & Pain Med, Munster, Germany
[2] Univ Hosp Muenster, Dept Med Hematol & Oncol A, Munster, Germany
[3] Univ Hosp Muenster, Inst Neuropathol, Munster, Germany
[4] Brown Univ, Dept Pathol & Lab Med, Providence, RI 02912 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
207
引用
收藏
页码:E448 / E448
页数:1
相关论文
共 50 条
  • [31] Enhanced BMP signaling through a type I BMP receptor ALK2 shows ectopic cartilage formation in mouse craniofacial portion
    Komatsu, Yoshihiro
    Fukuda, Tomokazu
    Scott, Gregory
    Kamiya, Nobuhiro
    Yamamura, Ken-ichi
    Mishina, Yuji
    DEVELOPMENTAL BIOLOGY, 2006, 295 (01) : 399 - 399
  • [32] ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development
    Zhang, DH
    Schwarz, EM
    Rosier, RN
    Zuscik, MJ
    Puzas, JE
    O'Keefe, RJ
    JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 (09) : 1593 - 1604
  • [33] BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis
    Komatsu, Yoshihiro
    Scott, Gregory
    Nagy, Andre
    Kaartinen, Vesa
    Mishina, Yuji
    DEVELOPMENTAL DYNAMICS, 2007, 236 (02) : 512 - 517
  • [34] Alk3, a BMP Type I Receptor Is Required for the Induction of Hepatic Hepcidin Gene Expression by Interleukin-6
    Steinbicker, Andrea U.
    Mayeur, Claire
    Lohmeyer, Lisa K.
    Leyton, Patricio
    Kao, Sonya M.
    Pappas, Alexandra E.
    Nobre, Rita
    Peterson, Randall T.
    Bloch, Donald B.
    Yu, Paul B.
    Bloch, Kenneth D.
    BLOOD, 2011, 118 (21) : 314 - 314
  • [35] A constitutively activated BMP receptor, ALK2, induces heterotopic bone formation in patients with Fibrodysplasia Ossificans Progressiva (FOP)
    Fukuda, T.
    Kohda, M.
    Kanomata, K.
    Nojima, J.
    Kamizono, J.
    Oda, H.
    Nakayama, K.
    Ohtake, A.
    Miyazono, K.
    Jimi, E.
    Owan, I.
    Okazaki, Y.
    Katagiri, T.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 : S10 - S10
  • [36] Different Domains Regulate Homomeric and Heteromeric Complex Formation among Type I and Type II Transforming Growth Factor-β Receptors
    Rechtman, Maya Mouler
    Nakaryakov, Alex
    Shapira, Keren E.
    Ehrlich, Marcelo
    Henis, Yoav I.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (12) : 7843 - 7852
  • [37] Transgenic mice with arterial smooth muscle cell-specific conditional deletion of the bone morphogenetic protein type IA receptor (BMPRIA/ALK3) are hyporesponsive to hypoxia
    El-Bizri, N
    Wang, LL
    Merklinger, SL
    Desai, K
    Rountree, RB
    Mishina, Y
    Rabinovitch, M
    CIRCULATION, 2004, 110 (17) : 132 - 132
  • [38] Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3
    Wang, Chia-Yu
    Xu, Yang
    Traeger, Lisa
    Dogan, Deniz Y.
    Xiao, Xia
    Steinbicker, Andrea U.
    Babitt, Jodie L.
    BLOOD, 2020, 135 (06) : 453 - 456
  • [39] The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6
    Mayeur, Claire
    Lohmeyer, Lisa K.
    Leyton, Patricio
    Kao, Sonya M.
    Pappas, Alexandra E.
    Kolodziej, Starsha A.
    Spagnolli, Ester
    Yu, Binglan
    Galdos, Rita L.
    Yu, Paul B.
    Peterson, Randall T.
    Bloch, Donald B.
    Bloch, Kenneth D.
    Steinbicker, Andrea U.
    BLOOD, 2014, 123 (14) : 2261 - 2268
  • [40] USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling
    Herhaus, Lina
    Al-Salihi, Mazin A.
    Dingwell, Kevin S.
    Cummins, Timothy D.
    Wasmus, Lize
    Vogt, Janis
    Ewan, Richard
    Bruce, David
    Macartney, Thomas
    Weidlich, Simone
    Smith, James C.
    Sapkota, Gopal P.
    OPEN BIOLOGY, 2014, 4 (05):