IDENTIFICATION OF ANTIPSYCHOTIC DRUG RESPONSE PHENOTYPES BY CLUSTERING LONGITUDINAL DATA: A CRITICAL STEP FOR PERSONALIZED MEDICINE

被引：0
|
作者：
Mas, S. [1 ,2 ,3 ]
Boloc, D. [4 ]
Torres, T. [1 ]
Martinez, A. [1 ]
Rodriguez, N. [1 ]
Parellada, M. [3 ,5 ]
Saiz-Ruiz, J. [3 ,6 ]
Cuesta, M. J. [3 ,7 ]
Gasso, P. [1 ]
Bernardo, M. [2 ,3 ,8 ]
Lafuente, A. [1 ,2 ,3 ]
机构：
[1] Univ Barcelona, Dept Med, Barcelona, Spain
[2] August Pi & Sunyer Biomed Res Inst IDIBAPS, Barcelona, Spain
[3] Carlos III Hlth Inst, Ctr Invest Biomed Red Salud Mental CIBERSAM, Madrid, Spain
[4] Univ Barcelona, Pharmacol Unit, Dept Clin Fdn, Barcelona, Spain
[5] Univ Complutense, IiSGM, Child & Adolescent Psychiat Dept, Hosp Gen Univ Gregorio Maranon,Sch Med, Madrid, Spain
[6] Univ Alcala, IRYCIS, Hosp Ramon y Cajal, Madrid, Spain
[7] Complejo Hospitalario Navarra, Inst Invest Sanitaria Navarra IdiSNA, Dept Psychiat, Pamplona, Spain
[8] Hosp Clin Barcelona, Barcelona Clin Schizophrenia Unit, Barcelona, Spain
来源：
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY | 2018年 / 123卷
关键词：
pharmacogenetics; personalized medicine; antipsychotics; clustering;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P157
引用
收藏
页码：94 / 94
页数：1
相关论文
共 50 条
  • [41] Cognitive impairment and response to antipsychotic drug treatment as intermediate phenotypes in schizophrenia: Integrating animal model, genetic and clinical trial approaches
    Meltzer, H.
    Oyamada, Y.
    Rajagopal, L.
    Li, J.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2014, 17 : 12 - 12
  • [42] Identification of Vaccine-Altered Circulating B Cell Phenotypes Using Mass Cytometry and a Two-Step Clustering Analysis
    Pejoski, David
    Tchitchek, Nicolas
    Pozo, Andre Rodriguez
    Elhmouzi-Younes, Jamila
    Yousfi-Bogniaho, Rahima
    Rogez-Kreuz, Christine
    Clayette, Pascal
    Dereuddre-Bosquet, Nathalie
    Levy, Yves
    Cosma, Antonio
    Le Grand, Roger
    Beignon, Anne-Sophie
    JOURNAL OF IMMUNOLOGY, 2016, 196 (11): : 4814 - 4831
  • [43] jmBIG: enhancing dynamic risk prediction and personalized medicine through joint modeling of longitudinal and survival data in big routinely collected data
    Bhattacharjee, Atanu
    Rajbongshi, Bhrigu Kumar
    Vishwakarma, Gajendra K.
    BMC MEDICAL RESEARCH METHODOLOGY, 2024, 24 (01)
  • [44] RESPONSE VARIATION AND TAILORED, ADAPTIVE INTERVENTIONS ARE CRITICAL FOR PERSONALIZED MEDICINE: EVIDENCE FROM THE RESIST-DIABETES STUDY
    Winett, Richard A.
    Davy, Brenda M.
    Savla, Jyoti T.
    Marinik, Elaina L.
    Winett, Sheila G.
    ANNALS OF BEHAVIORAL MEDICINE, 2014, 47 : S37 - S37
  • [45] SYSTEM-IDENTIFICATION BASED ON CLOSED-LOOP STEP RESPONSE DATA
    WANG, L
    CLUETT, WR
    IEE PROCEEDINGS-CONTROL THEORY AND APPLICATIONS, 1994, 141 (02): : 107 - 110
  • [46] Erratum to:Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine
    HONG HuiXiao
    ZHANG WenQian
    SHEN Jie
    SU ZhenQiang
    NING BaiTang
    HAN Tao
    PERKINS Roger
    SHI LeMing
    TONG WeiDa
    Science China(Life Sciences) , 2013, (03) : 291 - 291
  • [47] Erratum to:Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine
    HONG HuiXiao
    ZHANG WenQian
    SHEN Jie
    SU ZhenQiang
    NING BaiTang
    HAN Tao
    PERKINS Roger
    SHI LeMing
    TONG WeiDa
    Science China(Life Sciences), 2013, 56 (03) : 291
  • [48] Erratum to: Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine
    HuiXiao Hong
    WenQian Zhang
    Jie Shen
    ZhenQiang Su
    BaiTang Ning
    Tao Han
    Roger Perkins
    LeMing Shi
    WeiDa Tong
    Science China Life Sciences, 2013, 56 : 291 - 291
  • [49] Proteomic-Based Discovery of Predictive Biomarkers for Drug Therapy Response and Personalized Medicine in Chronic Immune Thrombocytopenia
    Gilanchi, Samira
    Faranoush, Mohammad
    Daskareh, Mahyar
    Sadjjadi, Fatemeh Sadat
    Zali, Hakimeh
    Ghassempour, Alireza
    Tavirani, Mostafa Rezaei
    BIOMED RESEARCH INTERNATIONAL, 2023, 2023
  • [50] Screening of Drug Resistance-Responsible Genes in Response to Personalized Medicine Using Patient-Derived Organoids
    Narue, Mie
    Sekine, Shigeki
    Nozaki, Hiroe
    Imai, Toshio
    Kassai, Hidetoshi
    CANCER SCIENCE, 2025, 116 : 1306 - 1306
12345