Palladium-catalyzed insertion-cyclization reaction of 2,3-dienyl alcohols with aryl iodides in water: Synthesis of 1-arylvinyl-substituted epoxides

被引：0
|
作者：
Yoshida, M [1 ]
Ishii, T [1 ]
Gotou, T [1 ]
Ihara, M [1 ]
机构：
[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Organ Chem, Sendai, Miyagi 9808578, Japan
来源：
HETEROCYCLES | 2004年 / 64卷
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A methodology for the synthesis of substituted epoxides in water has been described. The reactions of 2,3-dienyl alcohols with aryl iodides in the presence of palladium catalyst in water afford the 1-arylvinyl-substituted epoxides. It is clear that water-soluble ligand TPPDS is suitable for the reaction, and various epoxides are produced in moderate to good yields.
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页码：41 / 44
页数：4
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