Forward and reverse genetic approaches to synaptogenesis

被引：20
|
作者：
Broadie, K [1 ]
机构：
[1] Univ Utah, Dept Biol, Salt Lake City, UT 84112 USA
来源：
CURRENT OPINION IN NEUROBIOLOGY | 1998年 / 8卷 / 01期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
D O I：
10.1016/S0959-4388(98)80016-0
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Genetic approaches at the neuromuscular synapse are leading investigation into the mechanisms of synaptogenesis. The marriage of classical (forward) and reverse genetic techniques allows the isolation and analysis of novel proteins involved in synaptic maturation and the functional in vivo characterization of previously identified synaptic proteins. Of particular interest are recent advances using mouse reverse genetics and Drosophila forward genetics.
引用
收藏
页码：128 / 138
页数：11
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