A new samarium diiodide-mediated coupling reaction between N-acyl lactams and ketones or aldehydes

被引：22
|
作者：
Farcas, S [1 ]
Namy, JL [1 ]
机构：
[1] Univ Paris Sud, CNRS, Lab Catalyse Mol, ICMO, F-91405 Orsay, France
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 38期
关键词：
coupling reactions; acyl lactams; amidoketones; amidoketols; samarium diiodide;
D O I：
10.1016/S0040-4039(00)01137-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new SmI2-mediated coupling reaction between N-acyl lactams and ketones or aldehydes is reported. The ring opening of these imides with samarium diiodide gives acyl samarium species, which are trapped by ketones or aldehydes to yield amido alpha-ketols. With an excess of SmI2, in the presence of ethanol, the end products are amidoketones. (C) 2000 Elsevier Science Ltd. All rights reserved.
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页码：7299 / 7302
页数：4
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