Translocation t(1;10)(q21;q26) in a case of acute nonlymphocytic leukemia

被引：2
|
作者：
Terreros, MC
Quesada, M
Slavutsky, IR
机构：
[1] Hosp Neuropsiquiatr Especializado Dr Alejandro Kor, Area Citogenet, Serv Anat Patol, La Plata, Argentina
[2] Acad Nacl Med, Inst Invest Hematol Mariano R Castex, Dept Genet, Buenos Aires, DF, Argentina
来源：
ACTA HAEMATOLOGICA | 1998年 / 99卷 / 02期
关键词：
acute nonlymphocytic leukemia; chromosome abnormalities; hematologic malignancies; t(1; 10);
D O I：
10.1159/000040818
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chromosome banding studies carried out on bone marrow cells from a 16 year-old boy with an M1 acute nonlymphocytic leukemia (ANLL) revealed an unbalanced translocation involving chromosomes 1 and 10: der(10) t(1;10) (q21;q26) that results in a partial trisomy 1q between bands 1q21-1qter. Marker del(6)(q21) and trisomies of chromosomes 18, 21 and 22 were also observed. To our knowledge, this der(10) is the first to be reported in a patient with ANLL.
引用
收藏
页码：92 / 94
页数：3
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