1,5-Benzodiazepine derivatives of 3-arylsydnones:: synthesis and antimicrobial activity of 3-aryl-4-[2′-aryl-2′,4′,6′,7′-tetrahydro-(1′H)-1′,5′-benzodiazepine-4′-yl]sydnones

被引：54

作者：

Kavali, JR ^{[1
]}

Badami, BV ^{[1
]}

机构：

[1] Karnatak Univ, Post Grad Dept Studies Chem, Dharwad 580003, Karnataka, India

来源：

FARMACO | 2000年 / 55卷 / 05期

关键词：

benzodiazepine derivatives; 3-arylsydnones; antimicrobial activity;

D O I：

10.1016/S0014-827X(00)00061-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The alpha-beta-unsaturated ketones of 3-arylsydnones (Ia-y) were treated with 1,2-phenylenediamine to obtain the 3-aryl-4-[2'-aryl-2',4',6',7'-tetrahydro-(1'H)-1',5'-benzodiazepine-4'-yl]sydnones (IIa-y) in high yield. All the new compounds synthesised were screened for antibacterial and antifungal activities. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：406 / 409

页数：4

共 50 条

[21] Synthesis of new 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antimicrobial agents
Shridhar Malladi
Arun M. Isloor
S. K. Peethambar
Hoong Kun Fun
Medicinal Chemistry Research, 2013, 22 : 2654 - 2664
[22] 1-acetyl-1,2,3,4-tetrahydro-4-methyl-2,4-diphenyl-5H-1,5-benzodiazepine
Laavanya, P
Panchanatheswaran, K
Venkatraj, M
Jeyaraman, R
Marshall, W
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 1999, 55 : 1355 - 1357
[23] Mannich reaction using 3-arylsydnone derivatives:: Synthesis and antimicrobial studies of 3-aryl-4-[2′-(1"methylaminobenzamidazole)-thiazol-4′-yl] sydones and 1",3"-bis-{3-aryl-4-[(2′-aminomethyl) thiazol-4′-yl]sydnonyl} benzimidazole-2"-thiones
Kavali, JR
Badami, BV
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2003, 12 (03) : 249 - 252
[24] RESEARCH ON 1,5-BENZODIAZEPINE .7. SYNTHESIS OF DERIVATIVES OF 1H-PYRIDINO[2,3-B][1,5]BENZODIAZEPINE
DIBRACCIO, M
ROMA, G
BALBI, A
ERMILI, A
FARMACO-EDIZIONE SCIENTIFICA, 1985, 40 (06): : 391 - 403
[25] Synthesis of new 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antimicrobial agents
Malladi, Shridhar
Isloor, Arun M.
Peethambar, S. K.
Fun, Hoong Kun
MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (06) : 2654 - 2664
[26] 4-Aryl-1-hydrazino-5H-2,3-benzodiazepine and 1-aryl-4-hydrazino-5H-2,3-benzodiazepine in the synthesis of condensed [1,2]diazepines
Kharaneko, O. I.
Popov, V. Yu.
Bogza, S. L.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2013, 49 (02) : 317 - 324
[27] 4-Aryl-1-hydrazino-5H-2,3-benzodiazepine and 1-aryl-4-hydrazino-5H-2,3-benzodiazepine in the synthesis of condensed [1,2]diazepines
O. I. Kharaneko
V. Yu. Popov
S. L. Bogza
Chemistry of Heterocyclic Compounds, 2013, 49 : 317 - 324
[28] Crystal Structures of 1, 5-Diacetyl-2, 2, 4-trimethyl-1H-tetrahydro-1, 5-benzodiazepine (DARTMBD) and N5-Ethoxycarbonyl-2-methyl-2, 4-diphenyl-1H-tetrahydro-1, 5-benzodiazepine (ECRPMBD)
Kavitha, T.
Ponnuswamy, S.
Suguna, S.
Sakthivel, P.
Ponnuswamy, M. N.
MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 2012, 557 : 18 - 27
[29] Synthesis of 1-aryl-2-methyl-3-ethoxycarbonyl-1,4,5,6 - tetrahydro-4(1H)-pyridones and their derivatives
Mickevicius, V.
Bylinskaite, J.
Tetrahedron Letters, 37 (20):
[30] Epoxy resins based on the 1,2,3,4-tetrahydroquinoxaline and the 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine ring systems
Davies, J
Johncock, P
Jones, DA
POLYMER, 1999, 40 (17) : 4897 - 4906

← 1 2 3 4 5 →