First reported case of Lachnoanaerobaculum gingivalis bacteremia in an acute myeloid leukemia patient with oral mucositis during high dose chemotherapy

被引：3

作者：

Okada, Naoto ^{[1
,2
,10
]}

Murakami, Akikazu ^{[3
]}

Sato, Masami ^{[2
]}

Nakamura, Shingen ^{[4
]}

Fujii, Shiro ^{[5
]}

Sogabe, Kimiko ^{[5
]}

Takahashi, Mamiko ^{[5
]}

Okada, Asami ^{[6
]}

Abe, Akane ^{[2
]}

Fujii, Hideki ^{[7
]}

Abe, Masahiro ^{[5
]}

Azuma, Momoyo ^{[2
]}

Ishizawa, Keisuke ^{[1
,8
,9
]}

机构：

[1] Tokushima Univ Hosp, Dept Pharm, Tokushima, Japan

[2] Tokushima Univ Hosp, Dept Infect Control & Prevent, Tokushima, Japan

[3] Tokushima Univ Grad Sch, Grad Sch Biomed Sci, Dept Oral Microbiol, Tokushima, Japan

[4] Tokushima Univ, Dept Community Med & Med Sci, Grad Sch Biomed Sci, Tokushima, Japan

[5] Tokushima Univ Grad Sch, Inst Biomed Sci, Dept Hematol Endocrinol & Metab, Tokushima, Japan

[6] Tokushima Univ Grad Sch, Inst Biomed Sci, Dept Pediat, Tokushima, Japan

[7] Keio Univ Sch Med, Dept Biol, Yokohama, Japan

[8] Tokushima Univ, Dept Clin Pharmacol & Therapeut, Grad Sch Biomed Sci, Tokushima, Japan

[9] Tokushima Univ Hosp, Clin Res Ctr Dev Therapeut, Tokushima, Japan

[10] Tokushima Univ Hosp, Dept Pharm, 2-50-1 Kuramoto, Tokushima, 7708503, Japan

来源：

ANAEROBE | 2022年 / 76卷

基金：

日本学术振兴会;

关键词：

Lachnoanaerobaculum gingivalis; Bacteremia; Oral mucositis; Acute myeloid leukemia; MICROBIOME; RESISTANCE; COMMUNITY;

D O I：

10.1016/j.anaerobe.2022.102610

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Case description: Lachnoanaerobaculum gingivalis is an obligate anaerobe identified in a human dental plaque in 2019. Here, we report the first case of L. gingivalis bacteremia in a patient with oral mucositis during chemotherapy. L. gingivalis was confirmed by 16S rRNA gene analysis but not by MALDI-TOF-MS. Conclusion: During chemotherapy in patients with oral mucositis, we should consider the possibility of L. gingivalis bacteremia.

引用

页数：4

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