Palmitoylcarnitine, an important component of the repair system in the synaptosome membrane, in oxidative stress

被引：0
|
作者：
Tyurina, YY
Arduini, A
Tyurin, VA
Sokolova, TV
Arrigoni-Martelli, E
机构：
[1] Russian Acad Sci, IM Sechenov Evolut Physiol & Biochem Inst, St Petersburg 196140, Russia
[2] Univ G DAnnunzio, Chieti, Italy
[3] Sigma Tau Co, Dept Pharmacol, Pomezia, Rome, Italy
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1997年 / 123卷 / 06期
关键词：
synaptosomes; oxidative stress; palmitoylcarnitine; reacylation;
D O I：
10.1007/BF02458078
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Oxidative stress is accompanied by a considerable rise of palmitic acid incorporation into phosphatidylethanolamine of synaptosome membranes due to activation of lysophosphatidylethanolamine palmitoyltransferase and carnitine palmitoyltransferase. In the absence of ATP carnitine palmitoyltransferase plays an essential role in reacylation of phosphatidylethanolamine, and palmitoylcarnitine serves as a reserve pool of palmitoyl coenzyme A.
引用
收藏
页码：565 / 567
页数：3
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