Levothyroxine Improves Subjective Sleepiness in a Euthyroid Patient with Narcolepsy without Cataplexy

被引：2

作者：

Sobol, Danielle L. ^{[1
]}

Spector, Andrew R. ^{[1
]}

机构：

[1] Duke Univ, Sch Med, Durham, NC 27704 USA

来源：

JOURNAL OF CLINICAL SLEEP MEDICINE | 2014年 / 10卷 / 11期

关键词：

narcolepsy; levothyroxine; excessive daytime sleepiness; THYROTROPIN-RELEASING-HORMONE; DAYTIME SLEEPINESS; CANINE NARCOLEPSY;

D O I：

10.5664/jcsm.4210

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: We discuss the use of levothyroxine for excessive daytime sleepiness (EDS) and prolonged nocturnal sleep time in a euthyroid patient with narcolepsy. Methods: After failure of first-line narcolepsy treatments, a 48-year-old female began levothyroxine (25 mcg/day). After 12 weeks of treatment, the patient was evaluated for improvement in total sleep time and subjective daytime sleepiness assessed by Epworth Sleepiness Scale (ESS). Results: At baseline, ESS score was 16 and total sleep time averaged 16 h/day. After 12 weeks, ESS was 13 and reported total sleep time was 13 h/day. Conclusions: Levothyroxine improved EDS and total sleep time in a euthyroid patient with narcolepsy without cataplexy after 12 weeks without side effects.

引用

页码：1231 / 1232

页数：2

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