HIPEC in ovarian cancer: What should we expect?

被引：1

作者：

Picard, Leonie ^{[1
]}

Bourgin, Charlotte ^{[2
]}

Penault-Llorca, Frederique ^{[1
]}

Beguinot, Marie ^{[1
]}

Cornou, Caroline ^{[1
]}

Le Bouedec, Guillaume ^{[1
]}

Mouret-Reynier, Marie-Ange ^{[1
]}

Selle, Frederic ^{[3
]}

Pomel, Christophe ^{[1
]}

机构：

[1] Ctr Jean Perrin, 58 Rue Montalembert, F-63011 Clermont Ferrand, France

[2] Inst Cancerol Ouest, 15 Rue Andre Boguel, F-49055 Angers, France

[3] Hop Diaconesses, 12-18 Rue Sergent Bauchat, F-75012 Paris, France

来源：

BULLETIN DU CANCER | 2019年 / 106卷 / 11期

关键词：

HIPEC; Ovarian; Carcinomatosis; HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY; INTERVAL DEBULKING SURGERY; CYTOREDUCTIVE SURGERY; ONCOLOGY-GROUP; STAGE-III; DOUBLE-BLIND; CISPLATIN; BEVACIZUMAB; PACLITAXEL; MULTICENTER;

D O I：

10.1016/j.bulcan.2019.04.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The results of PRODIGE 7 study demonstrate that the use of HIPEC is not beneficial for patients in the treatment of colorectal carcinomatosis. Nevertheless, a recent study published in New England Journal of Medicine showed that hyperthermic intraperitoneal chemotherapy (HIPEC) increased overall survival for patients with ovarian peritoneal carcinomatosis. Although, the emergence of targeted therapies (anti-angiogenic agents, PARP-inhibitors, anti-PDL1) results in new standards of treatment in first line or recurrence disease. In this general context, what is the potential interest of HIPEC for the treatment of ovarian carcinoma?

引用

页码：1023 / 1028

页数：6

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