A novel pH-sensitive chiral amphiphile:: Synthesis, aggregation, and interaction with β-cyclodextrin

被引：22
|
作者：
Wang, CZ [1 ]
Gao, Q [1 ]
Huang, JB [1 ]
机构：
[1] Peking Univ, Inst Phys Chem, Beijing 100871, Peoples R China
来源：
LANGMUIR | 2003年 / 19卷 / 09期
关键词：
D O I：
10.1021/la0265878
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel pH-sensitive chiral amphiphile, N-(4-decyloxy-2-hydroxybenzylidene)-L-leucine, was synthesized. Two kinds of vesicles were found at different pH ranges, 6.5-8.0 and 11.5-12.5, and a helical structure was observed at pH = 11.0. This unique behavior can be attributed to the formation of a dimeric structure. The interaction between this amphiphile and beta-cyclodextrin was investigated by fluorescence emission spectra, H-1 NMR, and molecular modeling.
引用
收藏
页码：3757 / 3761
页数：5
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