Alcohols in direct carbon-carbon and carbon-heteroatom bond-forming reactions: recent advances

被引:25
|
作者
Ajvazi, Njomza [1 ]
Stavber, Stojan [1 ,2 ]
机构
[1] Jozef Stefan Int Postgrad Sch, Jamova 39, Ljubljana 1000, Slovenia
[2] Jozef Stefan Inst, Jamova 39, Ljubljana 1000, Slovenia
关键词
Alcohols; C-C or C-heteroatom bond formation; nucleophilic substitution; BETA-DICARBONYL COMPOUNDS; ONE-POT SYNTHESIS; NUCLEOPHILIC-SUBSTITUTION-REACTIONS; PI-ACTIVATED ALCOHOLS; CATALYZED DIRECT BENZYLATION; DIRECT COUPLING REACTION; MILD REACTION CONDITIONS; SECONDARY BENZYLIC ALCOHOLS; DIPHENYLMETHYL DPM ETHERS; FRIEDEL-CRAFTS ALKYLATION;
D O I
10.24820/ark.5550190.p010.237
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
In recent years, nucleophilic substitution of alcohols leading to the formation of the C-C and C-heteroatom bonds has become an attractive process used in the synthesis of organic compounds, offering a potential impact on the environment, since water is the only by-product of the reaction. A comprehensive compilation of methods for the activation and displacement of a hydroxyl group covering the last seventeen years is the objective of the present review.
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页码:288 / 329
页数:42
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