Effects of printing conditions on cell distribution within microspheres during inkjet-based bioprinting

被引:28
|
作者
Xu, Heqi [1 ]
Casillas, Jazzmin [2 ]
Xu, Changxue [1 ]
机构
[1] Texas Tech Univ, Dept Ind Mfg & Syst Engn, Lubbock, TX 79409 USA
[2] Texas Tech Univ, Dept Mech Engn, Lubbock, TX 79409 USA
基金
美国国家科学基金会;
关键词
SILK FIBROIN; TISSUE; CONSTRUCTS;
D O I
10.1063/1.5116371
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Inkjet-based bioprinting have been widely employed in a variety of applications in tissue engineering and drug screening and delivery. The typical bioink used in inkjet bioprinting consists of biological materials and living cells. During inkjet bioprinting, the cell-laden bioink is ejected out from the inkjet dispenser to form microspheres with cells encapsulated. The cell distribution within microspheres is defined as the distribution of cell number within the microspheres. The paper focuses on the effects of polymer concentration, excitation voltage, and cell concentration on the cell distribution within microspheres during inkjet printing of cell-laden bioink. The normal distribution has been utilized to fit the experimental results to obtain the mean and standard deviation of the distribution. It is found that the cell distribution within the microspheres increases with the increase of the cell concentration, sodium alginate concentration, and the excitation voltage.
引用
下载
收藏
页数:10
相关论文
共 50 条
  • [1] Optimizing cell deposition for inkjet-based bioprinting
    Ng, Wei Long
    Shkolnikov, Viktor
    INTERNATIONAL JOURNAL OF BIOPRINTING, 2024, 10 (02) : 182 - 206
  • [2] Investigation of Cell Aggregation on the Printing Performance in Inkjet-Based Bioprinting of Cell-Laden Bioink
    Xu, Heqi
    Liu, Jiachen
    Shahriar, Md
    Xu, Changxue
    LANGMUIR, 2023, 39 (01) : 545 - 555
  • [3] Polyvinylpyrrolidone-based bioink: influence of bioink properties on printing performance and cell proliferation during inkjet-based bioprinting
    Ng, Wei Long
    Huang, Xi
    Shkolnikov, Viktor
    Suntornnond, Ratima
    Yeong, Wai Yee
    BIO-DESIGN AND MANUFACTURING, 2023, 6 (06) : 676 - 690
  • [4] Polyvinylpyrrolidone-based bioink: influence of bioink properties on printing performance and cell proliferation during inkjet-based bioprinting
    Wei Long Ng
    Xi Huang
    Viktor Shkolnikov
    Ratima Suntornnond
    Wai Yee Yeong
    Bio-Design and Manufacturing, 2023, 6 (06) : 676 - 690
  • [5] Polyvinylpyrrolidone-based bioink: influence of bioink properties on printing performance and cell proliferation during inkjet-based bioprinting
    Wei Long Ng
    Xi Huang
    Viktor Shkolnikov
    Ratima Suntornnond
    Wai Yee Yeong
    Bio-Design and Manufacturing, 2023, 6 : 676 - 690
  • [6] Investigation and Characterization of Cell Aggregation During and After Inkjet-Based Bioprinting of Cell-Laden Bioink
    Xu, Heqi
    Salazar, Dulce Maria Martinez
    Shahriar, Md
    Xu, Changxue
    JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME, 2022, 144 (10):
  • [7] Predictive Modeling of Droplet Formation Processes in Inkjet-Based Bioprinting
    Wu, Dazhong
    Xu, Changxue
    JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME, 2018, 140 (10):
  • [8] Predictive Modeling of Droplet Velocity and Size in Inkjet-Based Bioprinting
    Wu, Dazhong
    Xu, Changxue
    Krishnamoorthy, Srikumar
    PROCEEDINGS OF THE ASME 13TH INTERNATIONAL MANUFACTURING SCIENCE AND ENGINEERING CONFERENCE, 2018, VOL 3, 2018,
  • [9] Investigation of Cell Concentration Change and Cell Aggregation Due to Cell Sedimentation during Inkjet-Based Bioprinting of Cell-Laden Bioink
    Xu, Heqi
    Salazar, Dulce Maria Martinez
    Xu, Changxue
    MACHINES, 2022, 10 (05)
  • [10] Inkjet and inkjet-based 3D printing: connecting fluid properties and printing performance
    Guo, Yang
    Patanwala, Huseini S.
    Bognet, Brice
    Ma, Anson W. K.
    RAPID PROTOTYPING JOURNAL, 2017, 23 (03) : 562 - 576