Enantioselective synthetic method for 3-hydroxyflavanones:: an approach to (2R,3R)-3′,4′-O-dimethyltaxifolin

被引：21
|
作者：
Jew, S [1 ]
Kim, H [1 ]
Bae, S [1 ]
Kim, J [1 ]
Park, H [1 ]
机构：
[1] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 41期
基金：
新加坡国家研究基金会;
关键词：
3-hydroxyflavanone; asymmetric dihydroxylation; intramolecular Mitsunobu reaction; (2R; 3R)-3; 4; '-O-dimethyltaxifolin;
D O I：
10.1016/S0040-4039(00)01382-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new enantioselective synthetic method for (2R,3R)-3-hydroxyflavanone (1a) was developed via asymmetric dihydroxylation (ADH) and intramolecular Mitsunobu reaction as key reactions and the application to synthesis of (2R,3R)-3',4'-O-dimethyltaxifolin (1b) is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：7925 / 7928
页数：4
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