Direct oxidative coupling of thiols and benzylic ethers via C(sp3)-H activation and C-O cleavage to lead thioesters

被引：21
|
作者：
Feng, J. [1 ]
Lv, M. -F. [1 ]
Lu, G. -P. [1 ]
Cai, C. [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Chem Engn Coll, Nanjing 210094, Jiangsu, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 03期
关键词：
SIMPLE ALKANES; H BONDS; CARBOXYLIC-ACIDS; IONIC LIQUID; THIOESTERIFICATION; FUNCTIONALIZATION; EFFICIENT; ALDEHYDES; ACYLATION; ESTERS;
D O I：
10.1039/c4ob02250e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An unprecedented C-S formation method via direct oxidative C(sp(3))-H bond functionalization and C-O cleavage of benzylic ethers was developed. Various thioesters including thioester structure containing drug intermediates could be achieved by this convenient, metal and base free method in satisfactory yields.
引用
收藏
页码：677 / 681
页数：5
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