Correlation between EGFR mutation T790M predominancy in initial biopsy detected by droplet digital PCR and acquired resistant mechanism to EGFR TKI.

被引：0
|
作者：
Koba, Hayato
Yoneda, Taro
Nishikawa, Shingo
Sone, Takashi
Kimura, Hideharu
Kasahara, Kazuo
机构：
[1] Kanazawa Univ, Dept Resp Med, Cellular Transplantat Biol, Grad Sch Med Sci, Kanazawa, Ishikawa, Japan
[2] Kanazawa Hosp, Kanazawa, Ishikawa, Japan
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2016年 / 34卷 / 15期
关键词：
D O I：
10.1200/JCO.2016.34.15_supll.e20602
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
e20602
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Use of Digital Droplet PCR for Detecting EGFR T790M Resistance Mutation in Plasma at Progression on TKI Therapy
    Jonsson, M.
    Planck, M.
    Reutersward, C.
    Nilsson, I.
    Carlsson, M.
    George, A.
    Saal, L.
    Staaf, J.
    Isaksson, S.
    JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S1037 - S1038
  • [2] Detection and quantification of EGFR T790M mutation in liquid biopsies by droplet digital PCR
    Silveira, Catarina
    Sousa, Ana Carla
    Janeiro, Andre
    Malveiro, Sara
    Teixeira, Encarnacao
    Brysch, Eva
    Pantarotto, Marcos
    Felizardo, Margarida
    Madureira, Rosa
    Nogueira, Fernando
    Guimaraes, Catia
    Matos, Cristina
    Canario, Dolores
    Bruges-Armas, Jacome
    Carmo-Fonseca, Maria
    TRANSLATIONAL LUNG CANCER RESEARCH, 2021, 10 (03) : 1200 - 1208
  • [3] Detection of T790M mutation in EGFR gene, an EGFR-TKI resistant mutation, in tumor samples unexposed to EGFR TKIs
    Koba, Hayato
    Kimura, Hideharu
    Nishikawa, Shingo
    Yoneda, Taro
    Sone, Takashi
    Kasahara, Kazuo
    CANCER RESEARCH, 2016, 76
  • [4] Droplet Digital PCR as a Molecular Tool for the Detection of the EGFR T790M Mutation in NSCLC Patients with the EGFR Activating Mutations
    Durgut, S.
    Salihefendic, L.
    Pecar, D.
    Ceko, I
    Mulahuseinovic, N.
    Izmirlija, M.
    Konjhodzic, R.
    BALKAN JOURNAL OF MEDICAL GENETICS, 2023, 26 (02) : 21 - 26
  • [5] Clinical implementation of plasma EGFR T790M testing using droplet digital PCR in TKI-resistant NSCLC patients
    Chan, Dana Leng Hui
    Toh, Grace Li Xian
    Goh, Liuh Ling
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2020, 116
  • [6] Noninvasive detection of acquired T790M mutation in NSCLC patients treated with EGFR-TKI using digital PCR of plasma
    Ishii, Hidenobu
    Azuma, Koichi
    Sakai, Kazuko
    Tokito, Takaaki
    Yamada, Kazuhiko
    Nishio, Kazuto
    Hoshibo, Tomoaki
    ANNALS OF ONCOLOGY, 2015, 26 : 138 - 138
  • [7] Correlation between re-biopsy site and detection of T790M mutation in NSCLC patients treated with EGFR TKI
    Shigematsu, Fumie
    Kogure, Yoshihito
    Saka, Hideo
    Yamada, Arisa
    Ishida, Akane
    Ise, Yuko
    Hori, Kazumi
    Oka, Saori
    Nakahata, Masashi
    Kitagawa, Chiyoe
    Oki, Masahide
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [8] Association Between EGFR T790M Status and Progression Patterns During Initial EGFR-TKI Treatment in Patients Harboring EGFR Mutation
    Oya, Yuko
    Yoshida, Tatsuya
    Kuroda, Hiroaki
    Shimizu, Junichi
    Horio, Yoshitsugu
    Sakao, Yukinori
    Inaba, Yoshitaka
    Hida, Toyoaki
    Yatabe, Yasushi
    CLINICAL LUNG CANCER, 2017, 18 (06) : 698 - +
  • [9] Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA
    Zhang, Rui
    Chen, Bojiang
    Tong, Xiang
    Wang, Ye
    Wang, Chengdi
    Jin, Jing
    Tian, Panwen
    Li, Weimin
    CANCER MANAGEMENT AND RESEARCH, 2018, 10 : 1209 - 1218
  • [10] EGFR TKI Treatment Induces Active Deamination of 5-Methylcytosine and Leads to Acquired T790M Resistant Mutation
    El Kadi, N.
    Wang, L.
    Davis, A.
    Brown, N.
    Kalemkerian, G.
    Hassan, K.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S1846 - S1847
12345