Use of Digital Droplet PCR for Detecting EGFR T790M Resistance Mutation in Plasma at Progression on TKI Therapy

被引:0
|
作者
Jonsson, M. [1 ]
Planck, M. [2 ]
Reutersward, C. [1 ]
Nilsson, I. [2 ]
Carlsson, M. [2 ]
George, A. [1 ]
Saal, L. [1 ]
Staaf, J. [1 ]
Isaksson, S. [1 ]
机构
[1] Div Oncol & Pathol, Dept Clin Sci Lund, Lund, Sweden
[2] Skane Univ Hosp, Dept Resp Med & Allergol, Lund, Sweden
关键词
plasma; EGFR; ddPCR;
D O I
10.1016/j.jtho.2019.08.2301
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
EP1.14-16
引用
收藏
页码:S1037 / S1038
页数:2
相关论文
共 50 条
  • [1] Detection and quantification of EGFR T790M mutation in liquid biopsies by droplet digital PCR
    Silveira, Catarina
    Sousa, Ana Carla
    Janeiro, Andre
    Malveiro, Sara
    Teixeira, Encarnacao
    Brysch, Eva
    Pantarotto, Marcos
    Felizardo, Margarida
    Madureira, Rosa
    Nogueira, Fernando
    Guimaraes, Catia
    Matos, Cristina
    Canario, Dolores
    Bruges-Armas, Jacome
    Carmo-Fonseca, Maria
    TRANSLATIONAL LUNG CANCER RESEARCH, 2021, 10 (03) : 1200 - 1208
  • [2] Optimal method for quantitative detection of plasma EGFR T790M mutation using droplet digital PCR system
    Suzawa, Ken
    Yamamoto, Hiromasa
    Ohashi, Kadoaki
    Hashida, Shinsuke
    Tomida, Shuta
    Kubo, Toshio
    Maki, Yuho
    Soh, Junichi
    Tsukuda, Kazunori
    Kiura, Katsuyuki
    Miyoshi, Shinichiro
    Toyooka, Shinichi
    ONCOLOGY REPORTS, 2017, 37 (05) : 3100 - 3106
  • [3] Clinical implementation of plasma EGFR T790M testing using droplet digital PCR in TKI-resistant NSCLC patients
    Chan, Dana Leng Hui
    Toh, Grace Li Xian
    Goh, Liuh Ling
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2020, 116
  • [4] Noninvasive detection of acquired T790M mutation in NSCLC patients treated with EGFR-TKI using digital PCR of plasma
    Ishii, Hidenobu
    Azuma, Koichi
    Sakai, Kazuko
    Tokito, Takaaki
    Yamada, Kazuhiko
    Nishio, Kazuto
    Hoshibo, Tomoaki
    ANNALS OF ONCOLOGY, 2015, 26 : 138 - 138
  • [5] Correlation between EGFR mutation T790M predominancy in initial biopsy detected by droplet digital PCR and acquired resistant mechanism to EGFR TKI.
    Koba, Hayato
    Yoneda, Taro
    Nishikawa, Shingo
    Sone, Takashi
    Kimura, Hideharu
    Kasahara, Kazuo
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [6] Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA
    Zhang, Rui
    Chen, Bojiang
    Tong, Xiang
    Wang, Ye
    Wang, Chengdi
    Jin, Jing
    Tian, Panwen
    Li, Weimin
    CANCER MANAGEMENT AND RESEARCH, 2018, 10 : 1209 - 1218
  • [7] Droplet Digital PCR as a Molecular Tool for the Detection of the EGFR T790M Mutation in NSCLC Patients with the EGFR Activating Mutations
    Durgut, S.
    Salihefendic, L.
    Pecar, D.
    Ceko, I
    Mulahuseinovic, N.
    Izmirlija, M.
    Konjhodzic, R.
    BALKAN JOURNAL OF MEDICAL GENETICS, 2023, 26 (02) : 21 - 26
  • [8] EGFR T790M Lung Cancer Mutation Detection by Digital Droplet PCR in Circulating Free Tumor DNA
    Hellwig, S.
    Welker, N.
    Vaughn, C.
    Akerley, W.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2015, 17 (06): : 829 - 829
  • [9] Analytical Comparison of Different Digital Droplet PCR (ddPCR) Reagents and Platforms for Detection of EGFR T790M Mutation
    Mills, J.
    Milosevic, D.
    Campion, M. B.
    Hailing, K. C.
    Liu, M. C.
    Highsmith, E. W.
    Kipp, B. R.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2016, 18 (06): : 1051 - 1051
  • [10] Diagnostic test accuracy of droplet digital PCR for the detection of EGFR mutation (T790M) in plasma: Systematic review and meta-analysis
    Liao, Yingyin
    Chen, Yuan
    Kou, Xiaoxia
    Xiao, Yi
    Ye, Junkai
    Wu, Aiwu
    CLINICA CHIMICA ACTA, 2020, 503 : 190 - 196