Endothelin receptor antagonists: which are the therapeutic perspectives in renal diseases?

被引:14
|
作者
Benigni, A [1 ]
Remuzzi, G [1 ]
机构
[1] Mario Negri Inst Pharmacol Res, I-24125 Bergamo, Italy
关键词
D O I
10.1093/ndt/13.1.5
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Since the discovery of endothelin peptides, much interdisciplinary research looked into their unique profile as powerful and long-lasting vasoconstrictors and mitogens. On account of the renal vasculature's sensitivity to endothelin-l and the peptide's various effects on the kidney, the role of endothelin-l in the control of kidney function has attracted particular attention.
引用
收藏
页码:5 / 7
页数:3
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