Pharmacogenetics of indirect anticoagulants: Value of genotype for improvement of efficacy and safety of therapy

被引：0
|
作者：
Sytchev, D. A.
Kropatcheva, E. S.
Ignatiev, I. V.
Bulytova, Yu. M.
Dobrovolsky, A. B.
Panchenko, E. P.
Kukes, V. G.
机构：
[1] IM Sechenov Med Acad, Moscow 119881, Russia
[2] AL Myasnikov Inst Clin Cardiol, Moscow 121552, Russia
[3] Inst Clin Pharmacol, Moscow, Russia
来源：
KARDIOLOGIYA | 2006年 / 46卷 / 07期
关键词：
pharmacogenetics; indirect anticoagulants; genetic polymorphism;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The review is devoted to the contemporary state of the problem of pharmacogenetics of indirect anticoagulants. At present there are data about effects of allele variants of CYP2C9, VKORC1, APOE genes on efficacy and safety of therapy with indirect anticoagulants. Detection of these variants is a perspective way to individualization of therapy with indirect anticoagulants.
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页码：72 / 77
页数：6
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