Sex disparities in cancer

被引：54
|
作者：
Zhu, Yizhi [1 ]
Shao, Xiaoyan [2 ]
Wang, Xueyan [1 ]
Liu Lingxiang [3 ]
Liang, Han [4 ]
机构：
[1] Nanjing Med Univ, Div Oncol, Nanjing 210000, Jiangsu, Peoples R China
[2] Nanjing Univ, Affiliated Drum Tower Hosp, Med Sch, Dept Hematol, Nanjing 210008, Jiangsu, Peoples R China
[3] Nanjing Med Univ, Affiliated Hosp 1, Dept Oncol, Nanjing 210029, Jiangsu, Peoples R China
[4] Univ Texas MD Anderson Canc Ctr, Dept Syst Biol, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA
来源：
CANCER LETTERS | 2019年 / 466卷
基金：
中国国家自然科学基金;
关键词：
Cancer incidence; Immune; Metabolism; DNA damage; Repair; GENE POLYMORPHISMS; LUNG-CANCER; BLADDER-CANCER; GENDER; RISK; ASSOCIATIONS; SUSCEPTIBILITY; SULT1A1; SMOKING;
D O I：
10.1016/j.canlet.2019.08.017
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Sex is a key biological factor affecting the development of many cancer types. There are considerable differences between male and female subpopulations in terms of cancer incidence, prognosis and mortality. Recent studies have extensively characterized the sex-biased molecular changes in cancer patients. Further efforts should be made to develop sex-specific cancer prevention and therapeutic strategies.
引用
收藏
页码：35 / 38
页数：4
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