Most effective stimulation site in subthalamic deep brain stimulation for Parkinson's disease

被引：201

作者：

Herzog, J

Fietzek, U

Hamel, W

Morsnowski, A

Steigerwald, F

Schrader, B

Weinert, D

Pfister, G

Müller, D

Mehdorn, HM

Deuschl, G

Volkmann, J

机构：

[1] Univ Kiel, Dept Neurol, D-24105 Kiel, Germany

[2] Univ Kiel, Dept Neurosurg, D-24105 Kiel, Germany

[3] Univ Kiel, Inst Expt & Appl Phys, D-24105 Kiel, Germany

[4] Univ Klinikum Eppendorf, Dept Neurol, Hamburg, Germany

来源：

MOVEMENT DISORDERS | 2004年 / 19卷 / 09期

关键词：

deep brain stimulation; subthalamic nucleus; Parkinson's disease; position; electrode;

D O I：

10.1002/mds.20056

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The optimal stimulation site in subthalamic deep brain stimulation (STN-DBS) was evaluated by correlation of the stereotactic position of the stimulation electrode with the electrophysiologically specified dorsal STN border. In a series of 25 electrodes, best clinical results with least energy consumption were found in contacts located in the dorsolateral border zone, whereas contacts within the subthalamic white matter, e.g., zona incerta, were significantly less effective. We suggest that the dorsolateral STN border should be covered by STN-DBS. (C) 2004 Movement Disorder Society.

引用

页码：1050 / 1054

页数：5

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