Staphylococcus aureus host cell invasion and post-invasion events

被引:120
|
作者
Sinha, Bhanu [1 ]
Fraunholz, Martin [2 ]
机构
[1] Univ Wurzburg, Inst Hyg & Microbiol, D-97080 Wurzburg, Germany
[2] Ernst Moritz Arndt Univ Greifswald, FunGene Competence Ctr Funct Genom, D-17487 Greifswald, Germany
关键词
Staphylococcus aureus; Invasion; Phagosomal escape; Intracellular persistence; Host cell death; alpha-Toxin; FIBRONECTIN-BINDING PROTEINS; HUMAN ENDOTHELIAL-CELLS; EPITHELIAL-CELLS; ALPHA-TOXIN; VIRULENCE FACTORS; HUMAN KERATINOCYTES; NASAL COLONIZATION; HUMAN NEUTROPHILS; TEICHOIC-ACIDS; DEATH PATHWAY;
D O I
10.1016/j.ijmm.2009.08.019
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Staphylococcus aureus is now recognized as a facultative intracellular pathogen. The aim of this review is to discuss novel data regarding the invasion mechanism and post-invasion events with a focus on the fate of the infected phagosome in non-professional phagocytes and the role of S. aureus alpha-toxin. (C) 2009 Elsevier GmbH. All rights reserved.
引用
收藏
页码:170 / 175
页数:6
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