Breast cancer proteomics: clinical perspectives

被引：6
|
作者：
Lau, Thomas Y. K. [1 ]
O'Connor, Darran P. [1 ]
Brennan, Donal J. [1 ]
Duffy, Michael J. [1 ]
Pennington, Stephen R. [1 ]
Gallagher, William M. [1 ]
机构：
[1] Natl Univ Ireland Univ Coll Dublin, Sch Biomol & Biomed Sci, Conway Inst, Dublin 4, Ireland
来源：
EXPERT OPINION ON BIOLOGICAL THERAPY | 2007年 / 7卷 / 02期
关键词：
biomarkers; breast cancer; proteomics; translational research;
D O I：
10.1517/14712598.7.2.209
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Breast cancer is the one of leading causes of cancer-related deaths in women within economically developed regions of the world. A major focus of present research into this malignancy is the identification of new biomarkers and drug targets to improve detection and treatment. Proteomics represents one of the latest technological developments in this context. It aims to analyse the complex circuitry of the breast cancer proteome. Here, the authors review how breast cancer proteomics has progressed so far, with emphasis on its potential application to clinically relevant scenarios.
引用
收藏
页码：209 / 219
页数：11
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