Role Medium-Chain Fatty Acids in the Lipid Metabolism of Infants

被引：24

作者：

Yuan, Tinglan ^{[1
,4
]}

Wang, Lei ^{[1
]}

Jin, Jun ^{[1
]}

Mi, Lijuan ^{[2
]}

Pang, Jinzhu ^{[2
]}

Liu, Zhengdong ^{[3
]}

Gong, Jinyan ^{[4
]}

Sun, Cong ^{[5
]}

Li, Jufang ^{[2
]}

Wei, Wei ^{[1
]}

Jin, Qingzhe ^{[1
]}

Wang, Xingguo ^{[1
]}

机构：

[1] Jiangnan Univ, Collaborat Innovat Ctr Food Safety & Qual Control, Sch Food Sci & Technol, Wuxi, Peoples R China

[2] Inner Mongolia Mengniu Dairy Grp Co Ltd, Beijing, Peoples R China

[3] Yashili Int Grp Co Ltd, Guangzhou, Peoples R China

[4] Zhejiang Univ Sci & Technol, Sch Biol & Chem Engn, Zhejiang Prov Key Lab Biol & Chem Proc Technol Far, Hangzhou, Peoples R China

[5] Henan Univ Technol, Coll Food Sci & Technol, Zhengzhou, Peoples R China

来源：

FRONTIERS IN NUTRITION | 2022年 / 9卷

关键词：

medium-chain fatty acids; human milk fat; infant formula; lipid metabolism; medium-chain triacylglycerols; DIETARY MEDIUM-CHAIN; BIRTH-WEIGHT INFANTS; LONG-CHAIN; HUMAN-MILK; PREMATURE-INFANTS; PRETERM INFANTS; TRIACYLGLYCEROL COMPOSITION; STRUCTURED TRIGLYCERIDES; LYMPHATIC ABSORPTION; GASTRIC LIPOLYSIS;

D O I：

10.3389/fnut.2022.804880

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Human breastmilk, the ideal food for healthy infants, naturally contains a high concentration of medium-chain fatty acids (MCFAs, about 15% of total fatty acids). MCFAs are an important energy source for infants due to their unique digestive and metabolic properties. MCFA-enriched oils are widely used in an infant formula, especially the formula produced for preterm infants. Recently, there has been a growing interest in the triglyceride structure of MCFAs in human milk, their metabolism, and their effects on infant health. This study summarized the MCFA composition and structure in both human milk and infant formula. Recent studies on the nutritional effects of MCFAs on infant gut microbiota have been reviewed. Special attention was given to the MCFAs digestion and metabolism in the infants. This paper aims to provide insights into the optimization of formulations to fulfill infant nutritional requirements.

引用

页数：7

共 50 条

[41] Postprandial Lipid Metabolism in Normolipidemic Subjects and Patients with Mild to Moderate Hypertriglyceridemia: Effects of Test Meals Containing Saturated Fatty Acids, Mono-Unsaturated Fatty Acids, or Medium-Chain Fatty Acids
Folwaczny, Alexander
Waldmann, Elisa
Altenhofer, Julia
Henze, Kerstin
Parhofer, Klaus G.
NUTRIENTS, 2021, 13 (05)
[42] In vivo absorption of medium-chain fatty acids by the rat colon exceeds that of short-chain fatty acids
Jorgensen, JR
Fitch, MD
Mortensen, PB
Fleming, SE
GASTROENTEROLOGY, 2001, 120 (05) : 1152 - 1161
[43] Recovery of volatile fatty acids from water using medium-chain fatty acids and a cosolvent
Rocha, Marisa A. A.
Raeissi, Sona
Hage, Patrick
Weggemans, Wilko M. A.
van Spronsen, Jaap
Peters, Cor J.
Kroon, Maaike C.
CHEMICAL ENGINEERING SCIENCE, 2017, 165 : 74 - 80
[44] ROLE OF MEDIUM-CHAIN TRIGLYCERIDES IN FORMULAS FOR PREMATURE-INFANTS
不详
NUTRITION REVIEWS, 1989, 47 (06) : 188 - 189
[45] Strategies for increasing Saccharomyces cerevisiae tolerance to medium-chain fatty acids
Besada-Lombana, Pamela Botero
Da Silva, Nancy
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
[46] Medium-chain fatty acids undergo elongation before β-oxidation in fibroblasts
Jones, Patricia M.
Butt, Yasmeen
Messmer, Bette
Boriak, Richard
Bennett, Michael J.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 346 (01) : 193 - 197
[47] Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail
Yang, Jeong-Yeh
Della-Fera, Mary Anne
Rayalam, Srujana
Park, Hea Jin
Ambati, Suresh
Hausman, Dorothy B.
Hartzell, Diane L.
Baile, Clifton A.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2009, 20 (07): : 537 - 543
[48] The use of saturated medium-chain fatty acids in wine production technology
Chvalinova, Klara
Baron, Mojmir
Sochor, Jiri
PROCEEDINGS OF 25TH INTERNATIONAL PHD STUDENTS CONFERENCE (MENDELNET 2018), 2018, : 270 - 274
[49] CUPHEA - A NEW PLANT SOURCE OF MEDIUM-CHAIN FATTY-ACIDS
GRAHAM, SA
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 1989, 28 (02) : 139 - 173
[50] ULTRAMICROMETHODS - PREPARATION OF DIAZOMETHANE - METHYLATION OF MEDIUM-CHAIN FATTY-ACIDS
HUWYLER, S
EXPERIENTIA, 1973, 29 (06): : 735 - 736

← 1 2 3 4 5 →