New diterpenoids from the octocoral Pachyclavularia violacea collected in Papua New Guinea

被引：26
|
作者：
Xu, L
Patrick, BO
Roberge, M
Allen, T
van Ofwegen, LP
Andersen, RJ
机构：
[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada
[2] Univ British Columbia, Dept Earth & Ocean Sci, Vancouver, BC V6T 1Z1, Canada
[3] Univ British Columbia, Dept Biochem & Mol Biol, Vancouver, BC V6T 1Z3, Canada
[4] Univ Alberta, Dept Pharmacol, Edmonton, AB T6G 2H7, Canada
[5] Museum Natl Hist Nat, Leiden, Netherlands
来源：
TETRAHEDRON | 2000年 / 56卷 / 46期
基金：
加拿大自然科学与工程研究理事会;
关键词：
Pachyclavularia violacea; diterpenoids; octocoral;
D O I：
10.1016/S0040-4020(00)00756-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Six new diterpenoids, pachyclavulariolides A (1) to F (6), with cembrane and briarane carbon skeletons have been isolated from specimens of Pachyclavularia violacea collected in Papua New Guinea. The structures of the new diterpenoids were elucidated by analysis of spectroscopic data. A single crystal X-ray diffraction analysis of pachyclavulariolide B (2) confirmed its structure. Pachyclavulariolide F (6) showed in vitro cytotoxicity. (C) 2000 Elsevier Science Ltd. All rights reserved.
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页码：9031 / 9037
页数：7
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