A ratiometric fluorescent probe for fast and sensitive detection of peroxynitrite: a boronate ester as the receptor to initiate a cascade reaction

被引：48
|
作者：
Zhou, Ji [1 ]
Li, Yang [1 ]
Shen, Jiaoning [1 ]
Li, Qiang [1 ]
Wang, Rui [1 ]
Xu, Yufang [1 ]
Qian, Xuhong [1 ]
机构：
[1] E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 93期
基金：
国家高技术研究发展计划(863计划);
关键词：
HYDROGEN-SULFIDE; NITRIC-OXIDE; REDOX CYCLES; SUPEROXIDE; OXIDATION; NEURONS;
D O I：
10.1039/c4ra10048d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A ratiometric fluorescent probe for the detection of peroxynitrite (ONOO-) was developed based on a boronate receptor and intramolecular cyclization. It features fast response, good selectivity and high sensitivity with a detection limit of 35 nM. The potential in bioimaging was exemplified in Hela cells.
引用
收藏
页码：51589 / 51592
页数：4
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