Tuberculosis and survival of HIV-infected individuals by time since seroconversion

被引：2

作者：

Glynn, Judith R. ^{[1
]}

Murray, Jill ^{[2
,3
]}

Shearer, Stuart ^{[5
]}

Sonnenberg, Pam ^{[4
]}

机构：

[1] Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England

[2] Natl Inst Occupat Hlth, Natl Hlth Lab Serv, Johannesburg, South Africa

[3] Univ Witwatersrand, Sch Publ Hlth, ZA-2050 Johannesburg, South Africa

[4] UCL, Res Dept Infect & Populat Hlth, London, England

[5] Gold Fields Ltd, Johannesburg, South Africa

来源：

AIDS | 2010年 / 24卷 / 07期

关键词：

ACTIVE ANTIRETROVIRAL THERAPY; GOLD-MINERS; COHORT; ADULTS; DEATH; DURATION; DISEASE;

D O I：

10.1097/QAD.0b013e328337b100

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a cohort of 1950 HIV-positive men with known dates of HIV seroconversion, 399 developed tuberculosis. Mortality rates following tuberculosis were greatly increased (hazard ratio, adjusted for age at seroconversion, 4.7, 95% confidence interval 3.7-6.1), and this ratio was similar at different times following seroconversion. Overall mortality was similar to that in western seroconverter cohorts with much lower rates of tuberculosis, suggesting that tuberculosis is more a marker of HIV progression than a cause of it.

引用

页码：1067 / 1069

页数：3

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