Peroxisomes: biochemistry, molecular biology and genetic diseases - a video programme for teaching students

被引：1
|
作者：
Latruffe, N [1 ]
Hassell, SJ [1 ]
机构：
[1] Univ Burgundy, LBMC, Fac Gabriel, F-21000 Dijon, France
来源：
BIOCHEMICAL EDUCATION | 2000年 / 28卷 / 03期
关键词：
D O I：
10.1016/S0307-4412(00)00005-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Peroxisome proliferation in rodent liver is a good biochemical marker of toxicology for several classes of xenobiotics, including fibrates: phthalates and adipates; or chlorophenoxy-acetate, a herbicide. Research in peroxisomes provides a good example of the integration of fields related to basic sciences and biomedical and industrial health. A 25 min video programme illustrates techniques involved in the characterization of purified preoxisomes and membranes, immunoblotting, measurement of proliferation markers, mRNA analysis at the post-transcriptional level, DNA techniques, cell cultures as biological models and computer analysis. It is aimed at undergraduates and non-biochemist advanced students in biology. (C) 2000 IUBMB. Published by Elsevier Science Ltd. All rights reserved.
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页码：136 / 138
页数：3
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