An improved process for the preparation of 4,4-dimethyloxazolidine-2-thione

被引:1
|
作者
Tewari, Neera [1 ]
Nair, Dinesh [1 ]
Nizar, Hashim [1 ]
Rai, Bishwa Prakash [1 ]
Prasad, Mohan [1 ]
机构
[1] Ranbaxy Res Labs, Div Chem Res, Gurgaon 122001, Haryana, India
关键词
D O I
10.1021/op6002677
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
An improved process for the preparation of 4,4-dimethyloxazolidine-2-thione (1), an auxiliary used in the synthesis of (3S,4S)-[(R)-1 '-((tert-butyldimethylsilyl)oxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone (2), a key intermediate for carbapenem synthesis is reported.
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页码:466 / 467
页数:2
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