Granulocyte colony-stimulating factor as the expecting sword for the treatment of severe sepsis

被引：14
|
作者：
Murata, A [1 ]
机构：
[1] Kyorin Univ, Sch Med, Dept Trauma & Crit Care Med, Tokyo 1818611, Japan
来源：
CURRENT PHARMACEUTICAL DESIGN | 2003年 / 9卷 / 14期
关键词：
D O I：
10.2174/1381612033454982
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Granulocyte colony-stimulating factor is a potent stimulator for neutrophils in the circulation as well as those progenitors to be increased and be grown in the bone marrow. Recombinant forms of this colony-stimulating factor, therefore, are widely using in the various kinds of clinical fields such as for the treatment of bone marrow Suppression after cancer chemotherapy and for the treatment of myelodysplastic disorders. One of the physiological function of granulocyte colony-stimulating factor is to activate neutrophils enough to flight against invaded microbes and others, thus it is hoped to be used for the treatment of various kinds of infectious diseases even while the host has a normal number of circulating neutrophils and normal bone marrow.
引用
收藏
页码：1115 / 1120
页数：6
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