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- [41] An Open-Label, Multicenter, 2-Arm, Dose-Finding, Phase 1b Study of the Combination of Ruxolitinib and Buparlisib (BKM120) in Patients with Myelofibrosis: Results from HARMONY StudyBLOOD, 2015, 126 (23)Durrant, Simon T.论文数: 0 引用数: 0 h-index: 0机构: Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaNagler, Arnon论文数: 0 引用数: 0 h-index: 0机构: Chaim Sheba Med Ctr, IL-52621 Tel Hashomer, Israel Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia论文数: 引用数: h-index:机构:Lavie, David论文数: 0 引用数: 0 h-index: 0机构: Hebrew Univ Jerusalem, Hadassah Med Org, Dept Hematol & Bone Marrow Transplantat, Jerusalem, Israel Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaChuah, Charles论文数: 0 引用数: 0 h-index: 0机构: Singapore Gen Hosp, Dept Hematol, Singapore, Singapore Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaPassamonti, Francesco论文数: 0 引用数: 0 h-index: 0机构: Osped Circolo & Fdn Macchi, Varese, Italy Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia论文数: 引用数: h-index:机构:le Coutre, Philipp论文数: 0 引用数: 0 h-index: 0机构: Med Klin MS Hamatol & Onkol, Berlin, Germany Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaGopalakrishna, Prashanth论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaMahuzier, Bruyere论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma SAS, Rueil Malmaison, France Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaMo, Shuyuan论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaMartinez-Lopez, Joaquin论文数: 0 引用数: 0 h-index: 0机构: Hosp 12 Octubre, E-28041 Madrid, Spain Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia
- [42] Phase I dose-escalation and -expansion study of buparlisib (BKM120), an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumorsINVESTIGATIONAL NEW DRUGS, 2014, 32 (04) : 670 - 681Rodon, Jordi论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ Hosp, Barcelona, Spain Univ Autonoma Barcelona, E-08193 Barcelona, Spain Vall dHebron Univ Hosp, Dept Med Oncol, Barcelona, Spain Vall dHebron Univ Hosp, Barcelona, SpainBrana, Irene论文数: 0 引用数: 0 h-index: 0机构: Vall dHebron Univ Hosp, Barcelona, Spain Univ Autonoma Barcelona, E-08193 Barcelona, Spain Vall dHebron Univ Hosp, Barcelona, SpainSiu, Lillian L.论文数: 0 引用数: 0 h-index: 0机构: Princess Margaret Canc Ctr, Toronto, ON, Canada Vall dHebron Univ Hosp, Barcelona, SpainDe Jonge, Maja J.论文数: 0 引用数: 0 h-index: 0机构: Erasmus MC Canc Inst, Rotterdam, Netherlands Vall dHebron Univ Hosp, Barcelona, SpainHomji, Natasha论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, Florham Pk, NJ USA Vall dHebron Univ Hosp, Barcelona, SpainMills, David论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Vall dHebron Univ Hosp, Barcelona, SpainDi Tomaso, Emmanuelle论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst BioMed Res Inc, Cambridge, MA USA Vall dHebron Univ Hosp, Barcelona, SpainSarr, Celine论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Vall dHebron Univ Hosp, Barcelona, SpainTrandafir, Lucia论文数: 0 引用数: 0 h-index: 0机构: Novartis Oncol, Paris, France Vall dHebron Univ Hosp, Barcelona, SpainMassacesi, Cristian论文数: 0 引用数: 0 h-index: 0机构: Novartis Oncol, Paris, France Vall dHebron Univ Hosp, Barcelona, SpainEskens, Ferry论文数: 0 引用数: 0 h-index: 0机构: Erasmus MC Canc Inst, Rotterdam, Netherlands Vall dHebron Univ Hosp, Barcelona, SpainBendell, Johanna C.论文数: 0 引用数: 0 h-index: 0机构: Sarah Cannon Res Inst, Nashville, TN USA Vall dHebron Univ Hosp, Barcelona, Spain
- [43] HARMONY: An Open-Label, Multicenter, 2-Arm, Dose-Finding, Phase 1b Study of the Combination of Ruxolitinib and Buparlisib (BKM120) in Patients with Myelofibrosis (MF)BLOOD, 2014, 124 (21)Durrant, Simon论文数: 0 引用数: 0 h-index: 0机构: Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaKoren-Michowitz, Maya论文数: 0 引用数: 0 h-index: 0机构: Chaim Sheba Med Ctr, Ramat Gan, Israel Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaLavie, David论文数: 0 引用数: 0 h-index: 0机构: Hadassah Med Ctr, IL-91120 Jerusalem, Israel Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaMartinez-Lopez, Joaquin论文数: 0 引用数: 0 h-index: 0机构: Hosp Univ 12 Octubre, Madrid, Spain Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia论文数: 引用数: h-index:机构:Passamonti, Francesco论文数: 0 引用数: 0 h-index: 0机构: Osped Circolo Varese, Varese, Italy Fdn Macchi, Varese, Italy Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaStalbovskaya, Viktoriya论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaAtienza, Edric论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaIommazzo, Dana论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharmaceut, E Hanover, NJ USA Univ Queensland, Royal Brisbane Hosp, Herston, Qld, AustraliaGopalakrishna, Prashanth论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Basel, Switzerland Univ Queensland, Royal Brisbane Hosp, Herston, Qld, Australia论文数: 引用数: h-index:机构:
- [44] Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue SarcomasPLOS ONE, 2015, 10 (09):Anderson, Jennifer L.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USAPark, Ann论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USAAkiyama, Ryan论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USATap, William D.论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, Dept Med, Div Solid Tumors, Sarcoma Med Oncol Serv, New York, NY 10021 USA Weill Cornell Med Coll, Dept Med, New York, NY USA Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USADenny, Christopher T.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USAFederman, Noah论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90024 USA Univ Calif Los Angeles, Dept Pediat, Div Hematol Oncol, Gwynne Hazen Cherry Mem Labs, Los Angeles, CA 90024 USA
- [45] Discovery of BKM120, a pan class I PI3 kinase inhibitor in phase I/II clinical trialsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240Burger, Matthew T.论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAPecchi, Sabina论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAWagman, Allan论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USANi, Zhi-Jie论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAKnapp, Mark论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAAtallah, Gordana论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAPfister, Keith论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USANg, Simon论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USASmith, Aaron论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAPick, Teresa论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAFrazier, Kelly论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAVerhagen, Joelle论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAZhang, Yanchen论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USABartulis, Sarah论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAHendricksen, Tom论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAIwanowicz, Edwin论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAHazenadar, Joshua论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAHuh, Kay论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAAshash, Ahmad论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAXin, Xiaohua论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAMenezes, Daniel论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAMerritt, Hanne论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAWiesmann, Marion论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USAVoliva, Charles论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst Biomed Res, Emeryville, CA USA Novartis Inst Biomed Res, Emeryville, CA USA
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- [50] Phase II trial of the phosphatidyinositol-3 kinase (PI3K) inhibitor BKM120 in recurrent glioblastoma (GBM)JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)Wen, Patrick Y.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAYung, W. K. Alfred论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAMellinghoff, Ingo K.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USALamborn, Kathleen论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USARamkissoon, Shakti论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USACloughesy, Timothy Francis论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USARinne, Mikael论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAOmuro, Antonio Marcilio Padula论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USADeAngelis, Lisa Marie论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAGilbert, Mark R.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAChi, Andrew S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USABatchelor, Tracy论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAColman, Howard论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAChang, Susan Marina论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAMassacesi, Cristian论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USADiTomaso, Emmanuelle论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAPrados, Michael论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USAReardon, David A.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USALigon, Keith L.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA 02115 USA