Initial outcomes with image-guided partial breast irradiation delivered with intensity-modulated radiation therapy

被引：7
|
作者：
Shah, Chirag [1 ]
Obi, Elizabeth [1 ]
Tom, Martin C. [1 ]
Manyam, Bindu, V [1 ]
Obi, Betty [1 ]
Al-Hilli, Zahraa [2 ]
Grobmyer, Stephen [2 ]
Abraham, Jame [1 ]
Xia, Ping [1 ]
Murray, Eric [1 ]
Cherian, Sheen [1 ]
Tendulkar, Rahul D. [1 ]
机构：
[1] Cleveland Clin, Taussig Canc Inst, Dept Radiat Oncol, Cleveland, OH 44195 USA
[2] Cleveland Clin, Dept Breast Surg, Digest Dis Inst, Cleveland, OH 44195 USA
来源：
BREAST JOURNAL | 2020年 / 26卷 / 02期
关键词：
breast cancer; breast conserving therapy; partial breast irradiation; CANCER; BRACHYTHERAPY; RADIOTHERAPY; LUMPECTOMY; ADOPTION; COST; RISK;
D O I：
10.1111/tbj.13544
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Patients were treated at a single institution to a dose of 30 Gy in five fractions delivered every other day using image-guided intensity modulated radiation therapy (IMRT) partial breast irradiation. A total of 34 patients were treated with a median follow-up of 4.6 months. The rate of acute Grade 1 dermatitis was 23.5% (n = 8), and Grade 1 fatigue was 17.6% (n = 6), with no Grade 2 or higher acute toxicities. The rate of chronic Grade 1 dermatitis was 25.0% (n = 6), Grade 1 fat necrosis 4.2% (n=1), with no patients demonstrating other chronic toxicities. Image-guided APBI delivered with IMRT is associated with low rates of acute and chronic toxicity though additional follow-up is warranted.
引用
收藏
页码：227 / 230
页数：4
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