Initial outcomes with image-guided partial breast irradiation delivered with intensity-modulated radiation therapy

被引：7

作者：

Shah, Chirag ^{[1
]}

Obi, Elizabeth ^{[1
]}

Tom, Martin C. ^{[1
]}

Manyam, Bindu, V ^{[1
]}

Obi, Betty ^{[1
]}

Al-Hilli, Zahraa ^{[2
]}

Grobmyer, Stephen ^{[2
]}

Abraham, Jame ^{[1
]}

Xia, Ping ^{[1
]}

Murray, Eric ^{[1
]}

Cherian, Sheen ^{[1
]}

Tendulkar, Rahul D. ^{[1
]}

机构：

[1] Cleveland Clin, Taussig Canc Inst, Dept Radiat Oncol, Cleveland, OH 44195 USA

[2] Cleveland Clin, Dept Breast Surg, Digest Dis Inst, Cleveland, OH 44195 USA

来源：

BREAST JOURNAL | 2020年 / 26卷 / 02期

关键词：

breast cancer; breast conserving therapy; partial breast irradiation; CANCER; BRACHYTHERAPY; RADIOTHERAPY; LUMPECTOMY; ADOPTION; COST; RISK;

D O I：

10.1111/tbj.13544

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Patients were treated at a single institution to a dose of 30 Gy in five fractions delivered every other day using image-guided intensity modulated radiation therapy (IMRT) partial breast irradiation. A total of 34 patients were treated with a median follow-up of 4.6 months. The rate of acute Grade 1 dermatitis was 23.5% (n = 8), and Grade 1 fatigue was 17.6% (n = 6), with no Grade 2 or higher acute toxicities. The rate of chronic Grade 1 dermatitis was 25.0% (n = 6), Grade 1 fat necrosis 4.2% (n=1), with no patients demonstrating other chronic toxicities. Image-guided APBI delivered with IMRT is associated with low rates of acute and chronic toxicity though additional follow-up is warranted.

引用

页码：227 / 230

页数：4

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