Performance of a New Al2O3/Ce-TZP Ceramic Nanocomposite Dental Implant: A Pilot Study in Dogs

被引：19

作者：

Lopez-Piriz, Roberto ^{[1
]}

Fernandez, Adolfo ^{[1
]}

Goyos-Ball, Lidia ^{[1
,2
]}

Rivera, Sergio ^{[2
]}

Diaz, Luis A. ^{[1
]}

Fernandez-Dominguez, Manuel ^{[3
]}

Prado, Catuxa ^{[1
]}

Moya, Jose S. ^{[1
]}

Torrecillas, Ramon ^{[1
]}

机构：

[1] Univ Oviedo, CSIC, Nanomat & Nanotechnol Res Ctr CINN, Avda Vega 4-6, El Entrego 33940, San Martin Del, Spain

[2] Nanoker Res, Pol Ind Olloniego, Parcela 22A,Nave 5, Oviedo 33660, Spain

[3] CEU San Pablo Univ, Madrid Monteprincipe Hosp, Dept Maxillofacial Surg, Madrid 28003, Spain

来源：

MATERIALS | 2017年 / 10卷 / 06期

关键词：

ceramic implant; nanocomposite; Ce-TZP; Al-TZP; zirconia implants; in vivo study; FRACTURE-TOUGHNESS; ZIRCONIA; TITANIUM; STRENGTH; SURVIVAL; ADHESION; ALUMINA;

D O I：

10.3390/ma10060614

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Although titanium remains as the prevalent material in dental implant manufacturing new zirconia-based materials that overcome the major drawbacks of the standard 3Y-yttria partially-stabilized zirconia (Y-TZP) are now emerging. In this study, a new ceramic nanocomposite made of alumina and ceria-stabilized TZP (ZCe-A) has been used to produce dental implants with the mechanic and topographic characteristics of a pilot implant design to evaluate bone and soft tissue integration in a dog model (n = 5). Histological cross-section analysis of the implanted ceramic fixations (n = 15) showed not only perfect biocompatibility, but also a high rate of osseous integration (defined as the percentage of bone to implant contact) and soft tissue attachment. This clinical success, in combination with the superior mechanical properties achieved by this Al2O3/Ce-TZP nanocomposite, may place this material as an improved alternative of traditional 3Y-TZP dental implants.

引用

页数：13

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