Photic stimulation-induced alteration of brain energy metabolism measured by 31P-MR spectroscopy in patients with MELAS

被引：17
|
作者：
Kato, T [1 ]
Murashita, J
Shioiri, T
Terada, M
Inubushi, T
Kato, N
机构：
[1] Univ Tokyo, Fac Med, Dept Neuropsychiat, Tokyo 113, Japan
[2] Shiga Univ Med Sci, Dept Internal Med 3, Otsu, Shiga 52021, Japan
[3] Shiga Univ Med Sci, Mol Neurobiol Res Ctr, Otsu, Shiga 52021, Japan
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 1998年 / 155卷 / 02期
关键词：
brain energy metabolism; MELAS (mitochondrial myopathy; encephalopathy; lactic acidosis; and stroke-like episodes); phosphocreatine; phosphorus-31 magnetic resonance spectroscopy (P-31-MRS); 3243 mitochondrial DNA mutation;
D O I：
10.1016/S0022-510X(97)00308-0
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We examined brain energy metabolism by phosphorus-31 magnetic resonance spectroscopy (P-31-MRS) in the occipital cortex in a mother and a daughter with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) during photic stimulation. The peak area ratio of phosphocreatine markedly decreased during photic stimulation, and subsequently increased after the stimulation. This method, photic stimulation-P-31-MRS, may be useful in assessing brain energy metabolism in neurological diseases. (C) 1998 Elsevier Science B.V.
引用
收藏
页码：182 / 185
页数：4
相关论文
共 50 条
  • [31] Quantitative analysis of energy metabolism in human muscle using SLOOP 31P-MR-spectroscopy
    Beer, M
    Schneider, C
    Köstler, H
    Buchner, S
    Sandstede, J
    Toyka, KV
    Hahn, D
    ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 2002, 174 (05): : 573 - 578
  • [32] ULTRASOUND INDUCED INCREASE IN MYOCARDIAL-CONTRACTILITY - METABOLIC EFFECTS MEASURED BY P-31 MR SPECTROSCOPY
    FORESTER, GV
    GEOFFRION, Y
    ROY, OZ
    SMITH, ICP
    BIOPHYSICAL JOURNAL, 1987, 51 (02) : A560 - A560
  • [33] Peripheral Glucose Metabolism and Brain Bioenergetics Measured by 31P Magnetic Resonance Spectroscopy in Unaffected Siblings of Patients With Psychotic Disorders
    Chouinard, Virginie Anne
    Du, Fei
    Kim, Sang-Young
    Man, Chiara Dalla
    Cobelli, Claudio
    Cypess, Aaron
    Valeri, Linda
    Ryan, Kyle
    Chouinard, Guy
    Henderson, David C.
    Cohen, Bruce M.
    Ongur, Dost
    NEUROPSYCHOPHARMACOLOGY, 2016, 41 : S577 - S578
  • [34] Effects of sleep deprivation:: The phosphorus metabolism in the human brain measured by 31P-magnetic resonance spectroscopy
    Murashita, J
    Yamada, N
    Kato, T
    Tazaki, M
    Kato, N
    PSYCHIATRY AND CLINICAL NEUROSCIENCES, 1999, 53 (02) : 199 - 201
  • [35] Effects of Olanzapine on Brain Energy Metabolism Measured by 31P-Magnetic Resonance Spectroscopy in Healthy Individuals Without History of Psychiatric Disorders
    Chouinard, Virginie-Anne
    Chen, Xi
    Gardner, Margaret E.
    Valeri, Linda
    Kuan, Elliot
    Cohen, Bruce M.
    Du, Fei
    Ongur, Dost
    BIOLOGICAL PSYCHIATRY, 2020, 87 (09) : S167 - S167
  • [36] Cognitive Impairment in Psychotic Disorders Is Associated with Brain Reductive Stress and Impaired Energy Metabolism as Measured by 31P Magnetic Resonance Spectroscopy
    Chouinard, Virginie-Anne
    Du, Fei
    Chen, Xi
    Tusuzian, Emma
    Ren, Boyu
    Anderson, Jacey
    Cuklanz, Kyle
    Feizi, Wirya
    Zhou, Shuqin
    Weerasekera, Akila
    Cohen, Bruce M.
    Ongur, Dost
    Lewandowski, Kathryn E.
    SCHIZOPHRENIA BULLETIN, 2025,
  • [37] MUSCLE ENERGY-METABOLISM IN FEMALE DMD BMD CARRIERS - A P-31-MR SPECTROSCOPY STUDY
    BARBIROLI, B
    FUNICELLO, R
    FERLINI, A
    MONTAGNA, P
    ZANIOL, P
    MUSCLE & NERVE, 1992, 15 (03) : 344 - 348
  • [38] ABNORMAL BRAIN ENERGY-METABOLISM ASSESSED BY P-31-MAGNETIC RESONANCE SPECTROSCOPY IN PATIENTS WITH LIVER-CIRRHOSIS
    BARBARA, L
    BARBIROLI, B
    GAIANI, S
    BOLONDI, L
    SOFIA, S
    LODI, R
    IOTTI, S
    ZANIOL, P
    SAMA, C
    BRILLANTI, S
    HEPATOLOGY, 1992, 16 (04) : A86 - A86
  • [39] RELATIONSHIP BETWEEN INTRACELLULAR PH AND ENERGY-METABOLISM IN DOG BRAIN AS MEASURED BY P-31-NMR
    NIOKA, S
    CHANCE, B
    HILBERMAN, M
    SUBRAMANIAN, HV
    LEIGH, JS
    VEECH, RL
    FORSTER, RE
    JOURNAL OF APPLIED PHYSIOLOGY, 1987, 62 (05) : 2094 - 2102
  • [40] H-1 IMAGE-GUIDED LOCALIZED P-31-MR SPECTROSCOPY OF HUMAN-BRAIN - QUANTITATIVE-ANALYSIS OF P-31-MR SPECTRA MEASURED ON VOLUNTEERS AND ON INTRACRANIAL TUMOR PATIENTS
    SEGEBARTH, CM
    BALERIAUX, DF
    DEBEER, R
    VANORMONDT, D
    MARIEN, A
    LUYTEN, PR
    DENHOLLANDER, JA
    MAGNETIC RESONANCE IN MEDICINE, 1989, 11 (03) : 349 - 366
12345