Evaluation of the Cepheid Xpert Xpress SARS-CoV-2 test for bronchoalveolar lavage

被引：4
|
作者：
Phan, Tung [1 ]
Mays, Ashley [2 ]
McCullough, Melissa [2 ]
Wells, Alan [1 ]
机构：
[1] Univ Pittsburgh, Dept Pathol, Pittsburgh, PA 15213 USA
[2] UPMC Hosp Syst, Clin Microbiol Lab, Pittsburgh, PA 15261 USA
来源：
JOURNAL OF CLINICAL VIROLOGY PLUS | 2022年 / 2卷 / 02期
关键词：
Evaluation; SARS-CoV-2; COVID-19; BAL; Cepheid;
D O I：
10.1016/j.jcvp.2022.100067
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Accurate and rapid laboratory tests are essential for the prompt diagnosis of COVID-19, which is important to patients and infection control. The Xpert Xpress SARS-CoV-2 test is a real-time RT-PCR intended for the qualitative detection of nucleic acid from SARS-CoV-2 in upper respiratory specimens. In this study, we assessed the analytical performance characteristics of this rapid test for SARS-CoV-2 in 60 bronchoalveolar lavage (BAL) specimens. BAL is a specimen type that is not authorized under EUA for the Xpert Xpress SARS-CoV-2 test. The limit of detection of the Xpert Xpress SARS-CoV-2 test was 500 copies/ml. The overall agreement of the Xpert Xpress SARS-CoV-2 test was 100%. The Xpert Xpress SARS-CoV-2 test is sensitive and specific to aid in diagnosis of COVID-19 using bronchoalveolar lavage.
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页数：3
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