Muscle MRI in Myotonic Dystrophy Type 1 with Foot Drop

被引:14
|
作者
Hamano, Tadanori [1 ]
Kawamura, Yasutaka [2 ]
Mutoh, Tatsuro [1 ,3 ]
Hirayama, Mikio [1 ,4 ]
Kuriyama, Masaru [1 ]
机构
[1] Univ Fukui, Fac Med Sci, Dept Internal Med 2, Eiheiji, Fukui 910193, Japan
[2] Univ Fukui, Fac Med Sci, Dept Radiol, Eiheiji, Fukui 910193, Japan
[3] Fujita Hlth Univ, Sch Med, Dept Neurol, Aichi, Japan
[4] Kasugai Municipal Hosp, Dept Neurol, Aichi, Japan
关键词
Myotonic dystrophy type 1; Muscle MRI; Foot drop;
D O I
10.1159/000280763
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The purpose of this study was to investigate the relationship of muscle MRI findings and gait disturbance in myotonic dystrophy type 1 (DM1) patients. Thirteen patients with DM1 were evaluated by manual muscle strength test and muscle MRI of the lower limb. All DM1 patients presenting with foot drop showed high intensity signals in the tibialis anterior muscles on T1-weighted imaging (p < 0.001). The patients presenting with gait disturbance showed high intensity signals in the semimembranosus, vastus intermedius and gastrocnemius medialis muscles, too. Disturbance of the gastrocnemius lateralis muscles was mild in all DM1 patients. The patients without gait disturbance showed no abnormalities, especially in tibialis anterior muscles on muscle MRI. Muscle MRI is useful for the detection of pathological muscles in DM1 patients with gait disturbance. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码:144 / 148
页数:5
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