THE EFFECT OF RESVERATROL TREATMENT ON HEART RATE AND QT VALUES IN RATS WITH CHRONIC FLUOROSIS

被引：0

作者：

Bulduk, Bahattin ^{[1
]}

Oto, Gokhan ^{[2
]}

Ozdemir, Hulya ^{[2
]}

Gunbatar, Nizamettin ^{[3
]}

Kocak, Yilmaz ^{[1
]}

Gul, Cihan ^{[1
]}

Bulduk, Mehmet ^{[3
]}

Elasan, Sadi ^{[4
]}

机构：

[1] Van Yuzuncu Yil Univ, Van Fac Hlth Sci, Dept Physiotherapy & Rehabil, TR-65080 Van, Turkey

[2] Van Yuzuncu Yil Univ, Fac Med, Dept Pharmacol & Toxicol, TR-65080 Van, Turkey

[3] Van Yuzuncu Yil Univ, Dept Nursing, Van Facuty Hlth Sci, TR-65080 Van, Turkey

[4] Van Yuzuncu Yil Univ, Fac Med, Dept Biostat, TR-65080 Van, Turkey

来源：

FRESENIUS ENVIRONMENTAL BULLETIN | 2022年 / 31卷 / 06期

关键词：

Fluorosis; Resveratrol; ECG; ELECTROCARDIOGRAM; POLYPHENOL; WINE;

D O I：

暂无

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

With this study, it was investigated how the impact of sodium fluoride (NaF) exposure on the cardiac conduction system would be treated with resveratrol. A total of 8 rats, 4 female and 4 male, weighing 200-300 grams, were used in each group. The first group was separated as the control group. The second group was determined as the group given 10 melt/day NaF, the third group as the group given 50 mg/It/day resveratrol, and the fourth group as the group given 10 mg/It/day NaF + 50 mg/It/day resveratrol. In the study conducted for 12 weeks, resveratrol and NaF were mixed into the drinking water of rats. When the study was finished after 4 months, the rats were anesthetized. They were placed in the right lateral position for the recording of ECGs. ECG samples were evaluated in II. derivation. Heart rate numbers were found high and QT values were found low in the groups that were administered only NaF. The heart rate and QT values of the groups administered with resveratrol alone or in combination with NaF showed parallelism with the control group.

引用

页码：5731 / 5735

页数：5

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