STATISTICAL ANALYSIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS IN CLINICAL STUDIES: EXPECTATIONS AND LIMITATIONS

被引：0

作者：

Gillissen, A. ^{[1
]}

Glaab, T. ^{[2
]}

Lewis, M. ^{[3
]}

Buhl, R. ^{[2
]}

Worth, H.

机构：

[1] Robert Koch Hosp, St George Med Ctr, Leipzig, Germany

[2] Univ Hosp, Dept Pulm, Mainz, Germany

[3] FISPE Epidemiol GmbH, Berlin, Germany

来源：

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 2009年 / 60卷

关键词：

chronic obstructive pulmonary disease; exacerbation; statistics; INHALED CORTICOSTEROIDS; LUNG-FUNCTION; FLUTICASONE PROPIONATE; COPD EXACERBATIONS; BETA-AGONISTS; MORTALITY; TIOTROPIUM; OUTCOMES; METAANALYSIS; SALMETEROL;

D O I：

暂无

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Acute exacerbations of chronic obstructive pulmonary disease (COPD) occur more frequently with increasing COPD severity and are associated with increased morbidity, reduced quality of life, and increased risk of mortality. The prevention and assessment of exacerbations, as a clinically and therapeutically relevant parameter, is a central aspect of clinical COPD studies. The aim of this review is to identify pittfalls in the analysis of the parameter of exacerbation and to describe the criteria that need to be considered in the statistical analysis of exacerbation studies.

引用

页码：7 / 11

页数：5

共 50 条

[21] Antibiotics for exacerbations of chronic obstructive pulmonary disease
Vollenweider, Daniela J.
Jarrett, Harish
Steurer-Stey, Claudia A.
Garcia-Aymerich, Judith
Puhan, Milo A.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2012, (12):
[22] Bacteria and exacerbations of chronic obstructive pulmonary disease
Anthonisen, NR
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (07): : 526 - 527
[23] Acute exacerbations of chronic obstructive pulmonary disease
Baghai-Ravary, R.
Quint, J. K.
Goldring, J. J. P.
Hurst, J. R.
Donaldson, G. C.
Wedzicha, J. A.
THORAX, 2007, 62 : A117 - A117
[24] Mechanisms of Chronic Obstructive Pulmonary Disease Exacerbations
Wedzicha, Jadwiga A.
ANNALS OF THE AMERICAN THORACIC SOCIETY, 2015, 12 : S157 - S159
[25] Defining exacerbations in chronic obstructive pulmonary disease
Hawkins, Padraig E.
Alam, Jamshed
McDonnell, Timothy J.
Kelly, Emer
EXPERT REVIEW OF RESPIRATORY MEDICINE, 2015, 9 (03) : 277 - 286
[26] Acute exacerbations of chronic obstructive pulmonary disease
Chabot, Francois
Gomez, Emmanuel
Guillaumot, Anne
Kheir, Ayman
Chaouat, Ari
PRESSE MEDICALE, 2009, 38 (03): : 485 - 495
[27] Predictors of chronic obstructive pulmonary disease exacerbations
Ishii, Takeo
Kida, Kozui
CURRENT OPINION IN PULMONARY MEDICINE, 2014, 20 (02) : 138 - 145
[28] Acute exacerbations of chronic obstructive pulmonary disease
Palm, KH
Decker, WW
EMERGENCY MEDICINE CLINICS OF NORTH AMERICA, 2003, 21 (02) : 331 - +
[29] The efficacy of corticosteroids in exacerbations of chronic obstructive pulmonary disease:: meta-analysis of published studies
Riancho, JA
Portero, I
Cubián, I
MEDICINA CLINICA, 2000, 114 (18): : 681 - 684
[30] Invasive Pulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease Exacerbations
Bulpa, Pierre
Duplaquet, Fabrice
Dimopoulos, George
Vogelaers, Dirk
Blot, Stijn
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 41 (06) : 851 - 861

← 1 2 3 4 5 →