Design and synthesis of a series highly potent and bioavailable FASN KR domain inhibitors for cancer

被引：3

作者：

Lu, Tianbao ^{[1
]}

Alexander, Richard ^{[1
]}

Bignan, Gilles ^{[1
]}

Bischoff, James ^{[1
]}

Connolly, Peter ^{[1
]}

Cummings, Max ^{[1
]}

De Breucker, Sabine ^{[2
]}

Esser, Norbert ^{[2
]}

Fraiponts, Erwin ^{[2
]}

Gilissen, Ron ^{[2
]}

Grasberger, Bruce ^{[1
]}

Janssens, Boudewijn ^{[2
]}

Ludovici, Donald ^{[1
]}

Meerpoel, Lieven ^{[2
]}

Meyer, Christophe ^{[3
]}

Parker, Michael ^{[1
]}

Peeters, Danielle ^{[2
]}

Schubert, Carsten ^{[1
]}

Smans, Karine ^{[2
]}

Van Nuffel, Luc ^{[2
]}

Vermeulen, Peter ^{[2
]}

机构：

[1] Janssen Res & Dev LLC, Spring House, PA USA

[2] Janssen Res & Dev LLC, Beerse, Belgium

[3] Janssen Res & Dev LLC, Val De Reuil, France

来源：

CANCER RESEARCH | 2014年 / 74卷 / 19期

关键词：

D O I：

10.1158/1538-7445.AM2014-4747

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

4747

引用

页数：2

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