Synthesis and Tuberculostatic Activity of Some 1,2,4-Triazines

被引：12

作者：

Shchegol'kov, E. V. ^{[1
]}

Khudina, O. G. ^{[1
]}

Ivanova, A. E. ^{[1
]}

Burgart, Ya. V. ^{[1
]}

Sadchikova, E. V. ^{[2
]}

Kravchenko, M. A. ^{[3
]}

Saloutin, V. I. ^{[1
]}

机构：

[1] Russian Acad Sci, Postovsky Inst Organ Synth, Ural Branch, Ekaterinburg, Russia

[2] Ural Fed Univ, Ekaterinburg, Russia

[3] Ural Res Inst Phthisiopulmonol, Ekaterinburg, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2014年 / 48卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

antituberculosis activity; 1,2,4-triazines; synthesis; DERIVATIVES; THIAZOLE;

D O I：

10.1007/s11094-014-1115-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antituberculosis activity of dihydrotriazolo[5,1-c][1,2,4]triazines, dihydropyrazolo[5,1-c][1,2,4]triazines, dihydroimidazolo[5,1-c][1,2,4]triazines, and dihydrotetrazolo[5,1-c][1,2,4]triazines was studied. A synthetic method for convenient synthons, 3-amino-1,2,4-triazines, was proposed. Their tuberculostatic activity was investigated.

引用

页码：383 / 386

页数：4

共 50 条

[41] SYNTHESIS AND ANTI-INFLAMMATORY EVALUATION OF 3-METHYLTHIO-1,2,4-TRIAZINES, 3-ALKOXY-1,2,4-TRIAZINES, AND 3-ARYLOXY-1,2,4-TRIAZINES
HEILMAN, WP
HEILMAN, RD
SCOZZIE, JA
WAYNER, RJ
GULLO, JM
ARIYAN, ZS
JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (03) : 282 - 287
[42] PREPARATION OF NEW 1,2,4-TRIAZINES
REPIC, O
MATTNER, PG
SHAPIRO, MJ
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1982, 19 (05) : 1201 - 1204
[43] SYNTHESIS AND CHARACTERIZATION OF SOME NEW 1,2,4-TRIAZINES CONTAINING 1,2,3-TRIAZOLE
Wang, Yan-Fei
Dong, Hong-ru
Li, Rong-Shan
Dong, Heng-Shan
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2012, 22 (01) : 81 - 84
[44] Synthesis and antimicrobial activities of condensed and uncondensed 1,2,4-triazines
Shaban, MAE
Taha, MAM
Hamouda, HMA
HETEROCYCLIC COMMUNICATIONS, 1998, 4 (04) : 351 - 359
[45] PHOTOCHEMICAL-SYNTHESIS OF 1,2,4-TRIAZINES AND THEIR CHEMICAL BEHAVIORS
SAITO, I
YAZAKI, A
MATSUURA, T
HETEROCYCLES, 1978, 9 (01) : 102 - 102
[46] SYNTHESIS AND REACTIONS OF SOME 6-(2-HYDROXY-1-NAPHTHYL)-1,2,4-TRIAZINES
EID, MM
KADRY, AM
HASSAN, RA
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (04) : 1117 - 1118
[47] Novel one pot synthesis of substituted 1,2,4-triazines
Phucho, T.
Nongpiur, A.
Tumtin, S.
Nongrum, R.
Myrboh, B.
Nongkhlaw, R. L.
ARKIVOC, 2008, : 79 - 87
[48] Synthesis of hydroxo derivatives and thiohydroxo derivatives of 1,2,4-triazines
Andreichikov, YS
Koltsova, SV
Zhikina, IA
Nekrasov, DD
ZHURNAL ORGANICHESKOI KHIMII, 1999, 35 (10): : 1567 - 1573
[49] Novel one pot synthesis of substituted 1,2,4-triazines
Nongkhlaw, RL
Myrboh, B
HETEROCYCLIC COMMUNICATIONS, 2006, 12 (01) : 67 - 72
[50] SYNTHESIS AND STRUCTURE OF PYRIMIDO-1,2,4-TRIAZINES
IBRAHIM, YA
ELWAHY, AHM
GAD, SAA
POLISH JOURNAL OF CHEMISTRY, 1994, 68 (06) : 1115 - 1121

← 1 2 3 4 5 →