Synthesis and Tuberculostatic Activity of Some 1,2,4-Triazines

被引：12
|
作者：
Shchegol'kov, E. V. [1 ]
Khudina, O. G. [1 ]
Ivanova, A. E. [1 ]
Burgart, Ya. V. [1 ]
Sadchikova, E. V. [2 ]
Kravchenko, M. A. [3 ]
Saloutin, V. I. [1 ]
机构：
[1] Russian Acad Sci, Postovsky Inst Organ Synth, Ural Branch, Ekaterinburg, Russia
[2] Ural Fed Univ, Ekaterinburg, Russia
[3] Ural Res Inst Phthisiopulmonol, Ekaterinburg, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2014年 / 48卷 / 06期
基金：
俄罗斯基础研究基金会;
关键词：
antituberculosis activity; 1,2,4-triazines; synthesis; DERIVATIVES; THIAZOLE;
D O I：
10.1007/s11094-014-1115-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The antituberculosis activity of dihydrotriazolo[5,1-c][1,2,4]triazines, dihydropyrazolo[5,1-c][1,2,4]triazines, dihydroimidazolo[5,1-c][1,2,4]triazines, and dihydrotetrazolo[5,1-c][1,2,4]triazines was studied. A synthetic method for convenient synthons, 3-amino-1,2,4-triazines, was proposed. Their tuberculostatic activity was investigated.
引用
收藏
页码：383 / 386
页数：4
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