Reflectance confocal endomicroscope with optical axial scanning for in vivo imaging of the oral mucosa

被引：17

作者：

Jabbour, Joey M. ^{[1
]}

Bentley, Julie L. ^{[2
]}

Malik, Bilal H. ^{[1
]}

Nemechek, John ^{[3
]}

Warda, John ^{[4
]}

Cuenca, Rodrigo ^{[1
]}

Cheng, Shuna ^{[1
]}

Jo, Javier A. ^{[1
]}

Maitland, Kristen C. ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA

[2] Univ Rochester, Inst Opt, Rochester, NY 14620 USA

[3] Metrol Concepts LLC, Rochester, NY 14623 USA

[4] Opt Technol Inc, New York, NY 14534 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2014年 / 5卷 / 11期

基金：

美国国家卫生研究院;

关键词：

ELECTRICALLY TUNABLE LENS; MICROSCOPY; TISSUES;

D O I：

10.1364/BOE.5.003781

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper presents the design and evaluation of a reflectance confocal laser endomicroscope using a miniature objective lens within a rigid probe in conjunction with an electrically tunable lens for axial scanning. The miniature lens was characterized alone as well as in the endoscope across a 200 mu m axial scan range using the tunable lens. The ability of the confocal endoscope to probe the human oral cavity is demonstrated by imaging of the oral mucosa in vivo. The results indicate that reflectance confocal endomicroscopy has the potential to be used in a clinical setting and guide diagnostic evaluation of biological tissue. (C) 2014 Optical Society of America

引用

页码：3781 / 3791

页数：11

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