Stationary solutions for a modified Peyrard-Bishop DNA model with up to third-neighbor interactions

被引:3
|
作者
Rapti, Z. [1 ]
机构
[1] Univ Illinois, Dept Math, Urbana, IL 61801 USA
来源
EUROPEAN PHYSICAL JOURNAL E | 2010年 / 32卷 / 02期
关键词
DYNAMICS; DENATURATION; ENERGETICS; MECHANICS; PATHWAYS;
D O I
10.1140/epje/i2010-10618-y
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We investigate a DNA model that takes into account stacking interactions with neighbors up to three bases away. The model is a generalization of the well-known Peyrard-Bishop (PB) model and is motivated by studies that suggest that nearest-neighbor models for base-pair interaction in a DNA chain might not be enough to capture the mechanism and dynamics of DNA base-pair opening. We study stationary solutions of the modified model and investigate their stability. A comparison with the PB model reveals that under a wide range of parameter values the main characteristics of the original model --such as the hyperbolicity of the equilibrium at the origin-- are preserved, but new types of stationary solutions emerge.
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页码:209 / 216
页数:8
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