Multifocal osteogenic sarcoma in Paget's disease

被引:7
|
作者
Vuillemin-Bodaghi, V
Parlier-Cuau, C
Cywiner-Golenzer, C
Quillard, A
Kaplan, G
Laredo, JD
机构
[1] Hop Lariboisiere, Serv Radiol Osteoarticulaire, Dept Bone & Joint Radiol, F-75010 Paris, France
[2] Lariboisiere Teaching Hosp, Dept Pathol, Paris, France
[3] St Antoine Teaching Hosp, Dept Rheumatol, Paris, France
关键词
Paget's disease; ilium; tibia; calvarium; osteosarcoma; multifocal;
D O I
10.1007/s002560000214
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The most serious complication of Pager's disease is sarcomatous degeneration of pagetic bone. Multifocal sarcomatous degeneration occurs mainly in polyostotic Paget's disease. Multifocal Pager's sarcoma is uncommon and can arise in any site. We report two cases of synchronous multifocal sarcomatous degeneration. The two patients were elderly women (aged 77 and 86 years, respectively) who developed sarcomatous lesions concomitantly, in the first case report in left ilium, left tibia, and first lumbar vertebra and in the second case report in the skull, right ilium, and sacrum. Whether these cases are due to the simultaneous development of several primaries or to metastases from a single primary remains unclear.
引用
收藏
页码:349 / 353
页数:5
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