An antitumor pectic polysaccharide from Feronia limonia

被引：46
|
作者：
Saima, Y
Das, AK
Sarkar, KK
Sen, AK
Sur, P
机构：
[1] Indian Inst Chem Biol, Dept Chem, Kolkata 700032, W Bengal, India
[2] Indian Inst Chem Biol, Dept Pharmacol, Kolkata 700032, W Bengal, India
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2000年 / 27卷 / 05期
关键词：
antitumor activity; Feronia limonia; rhamnogalacturonan;
D O I：
10.1016/S0141-8130(00)00134-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An acidic heteropolysaccharide has been isolated from the tropical angiosperm Feronia limonia syn. F. elephantum (family: Rutaceae). A partially carboxymethylated alpha-(1-4) polygalacturonan backbone structure with 2- and 2,4-O-alpha-L-rhamnopyranosyl, 2- and 2,3-O-alpha-L-arabinofuranosyl and 3-, 2,4-and terminal alpha-D-galactopyranosyl bearing side chains has been tentatively assigned. The preliminary study in the murine model showed some significant in vivo Ehrlich ascites carcinoma cell growth inhibition. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：333 / 335
页数：3
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