An asymmetric total synthesis of (+)-(3R,4S,5R,7S)-neoclansenamide

被引:16
|
作者
Wang, JQ [1 ]
Tian, WS [1 ]
机构
[1] ACAD SINICA,SHANGHAI INST ORGAN CHEM,SHANGHAI 200032,PEOPLES R CHINA
关键词
D O I
10.1039/p19960000209
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new hepatoprotective lactam (+)-(3R,4S,5R,7S)-neoclausenamide 1 isolated from the leaves of Chinese folk medicine Clausena lansium (Lour.) Skeel, has been readily synthesized from methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate in 22.0% overall yield.
引用
收藏
页码:209 / 212
页数:4
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